iowaodes

Genetic Evaluation of kids with congenital ocular anomalies in three ecological areas of Nepal

Next generation sequencing reveals a novel pathogenic variant in the ATMgene

 

Introduction: Ataxia telangiectasia (A-T) is a uncommon autosomal recessive multisystemic illness. Sufferers with the A-T syndrome current a broad spectrum of illness phenotypes. The ATM (ataxia telangiectasia mutated) gene, the one causative gene for A-T.

 

Methodology: A affected person of Persian origin presenting with typical A-T was referred to our genetics middle for specialised genetic counseling and testing. Focused next-generation sequencing (NGS) was utilized. Sanger sequencing was used to substantiate the candidate variant. Modeling was carried out utilizing the SWISS-MODEL server.Outcomes: A homozygous stop-gain variant c.829G > T (p.E277*) was discovered within the ATM gene. This variant was confirmed by Sanger sequencing and modeling of native construction and truncated construction was carried out.

 

Conclusion: Thus far, only a few pathogenic variants of the ATM gene have been reported from the Iranian inhabitants. The discovering has implications in molecular diagnostic for A-T in Iran.

iowaodes
iowaodes

 

Cat IgG Fab2-Biotin conjugate (non-immune, isotype control) purified

20002-4-B 0.1 mg
EUR 225.00

Cat IgG Fab2-FITC conjugate (non-immune, isotype control) purified

20002-4-F 0.1 mg
EUR 225.00

Cat IgG Fab2-HRP conjugate (non-immune, isotype control) purified

20002-4-HP 0.1 mg
EUR 225.00

Cat IgG Fab2, unlabeled (non-immune, isotype control) purified

20002-4-UL 0.1 mg
EUR 164.00

Cat IgM-Biotin conjugate (non-immune, isotype control) purified

20002-5-B 0.1 mg
EUR 225.00

Cat IgM, unlabeled (non-immune, isotype control) purified

20002-5-UL 0.1 mg
EUR 164.00

FluoroQuest™ Anti-fading Kit II *Optimized for Plate Imaging*

20003 1 kit
EUR 132.00
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Hamster IgG, purified (Syrian, isotype control)

20003-1 1 mg
EUR 141.00

Hamster IgG-Biotin conjugate, isotype control (Syrian)

20003-1-B 100 test
EUR 164.00

Hamster IgG-Cy5 conjugate, isotype control (Syrian)

20003-1-Cy5 50 tests
EUR 225.00

Hamster IgG-FITC conjugate, isotype control (Syrian)

20003-1-F 100 tests
EUR 164.00

Hamster IgG-HRP conjugate, isotype control (Syrian)

20003-1-HP 100 tests
EUR 164.00

Hamster IgG-R-PE-Cy5.5 conjugate, isotype control (Syrian)

20003-1-PC5 50 tests
EUR 250.00

Hamster IgG-R-PE conjugate, isotype control (Syrian)

20003-1-PE 50 tests
EUR 225.00

Hamster IgG, purified (Armenian, Isotype control)

20003-1AH 1 mg
EUR 263.00

Hamster (Syrian, non-immune) Serum IgM, purified (Syrian)

20003-2-1 0.5 mg
EUR 225.00

FluoroQuest™ Mounting Medium with DAPI

20004 50 mL
EUR 132.00
  • R-phrase: R20, R21, R68
  • H-Phrase: H303, H313, H340
  • Symbol for dangerous compounds: T
  • UNSPEC Code: 12352200

G. Pig IgG, purified (non-immune, serum, Isotype control)

20004-1 1 mg
EUR 141.00

G. Pig IgM, purified (non-immune, serum, Isotype control)

20004-2-1 0.5 mg
EUR 225.00

G. Pig IgG Fc-Biotin conjugate (isotype control, non-immune) purified

20004-3-B 0.1 mg
EUR 225.00

G. Pig IgG Fc-FITC conjugate (isotype control, non-immune) purified

20004-3-F 0.1 mg
EUR 225.00

G. Pig IgG Fc-HRP conjugate (isotype control, non-immune) purified

20004-3-HP 0.1 mg
EUR 225.00

G. Pig IgG Fc unlabeled (isotype control, non-immune) purified

20004-3-UL 0.5 mg
EUR 202.00

G. Pig IgA, purified (non-immune, serum, Isotype control)

20004-5-1 100 ug
EUR 347.00

G. Pig IgG-Biotin conjugate (isotype control)

20004-B 100 ug
EUR 202.00

G. Pig IgG-FITC conjugate (isotype control)

20004-F 100 ug
EUR 202.00

G. Pig IgG-HRP conjugate (isotype control)

20004-HP 100 ug
EUR 202.00

Rat IgG, purified (Whole, non-immune) (isotype control)

20005-1 1 mg
EUR 141.00

Rat IgG purified (isotype control)

20005-1-200 0.5 ml
EUR 103.00

Rat IgG Fab fragment, purified (isotype control)

20005-1-FAB 1 mg
EUR 164.00

Rat IgG F(ab')2 fragment, purified (isotype control)

20005-1-FAB2 1 mg
EUR 202.00

Rat IgG (Fc) fragment, purified (isotype control)

20005-1-FC 0.5 mg
EUR 250.00

Rat IgG (Fc)-Biotin Conjuagte (isotype control), purified

20005-1-FC-B 0.1 mg
EUR 225.00

Rat IgG (Fc)-FITC Conjuagte (isotype control), purified

20005-1-FC-F 0.1 mg
EUR 225.00

Rat IgG (Fc)-HRP Conjuagte (isotype control), purified

20005-1-FC-HP 0.1 mg
EUR 225.00

Rat IgG, purified (Whole, non-immune) (isotype control)

20005-10 10 mg
EUR 408.00

Rat IgG1 cunonjugated (isotype control)

20005-11 100 ug
EUR 164.00

Rat IgG1-Biotin conjugate (isotype control)

20005-11-B 100 ug
EUR 202.00

Rat IgG1-FITC conjugate (isotype control)

20005-11-F 100 ug
EUR 225.00

Rat IgG1-HRP conjugate (isotype control)

20005-11-HP 100 ug
EUR 202.00

Rat IgG1-R-PE-Cy5.5 conjugate (isotype control)

20005-11-PC5 25 tests
EUR 202.00

Rat IgG1-R-PE conjugate (isotype control)

20005-11-PE 25 tests
EUR 202.00

Rat IgG2a unconjugated (isotype control)

20005-12 100 ug
EUR 164.00

Rat IgG2a-APC conjugate (isotype control)

20005-12-APC 25 tests
EUR 202.00

Rat IgG2a-Biotin conjugate (isotype control)

20005-12-B 100 ug
EUR 202.00

Rat IgG2a-FITC conjugate (isotype control)

20005-12-F 100 ug
EUR 225.00

Rat IgG2a-HRP conjugate (isotype control)

20005-12-HP 100 ug
EUR 202.00

Rat IgG2a-R-PE-Cy5.5 conjugate (isotype control)

20005-12-PC5 25 tests
EUR 213.00

Rat IgG2a-R-PE conjugate (isotype control)

20005-12-PE 25 tests
EUR 202.00

Rat IgG2b unconjugated (isotype control)

20005-13 100 ug
EUR 164.00

Rat IgG2b-Biotin conjugate (isotype control)

20005-13-B 100 ug
EUR 202.00

Rat IgG2b-FITC conjugate (isotype control)

20005-13-F 100 ug
EUR 225.00

Rat IgG2b-HRP conjugate (isotype control)

20005-13-HP 100 ug
EUR 202.00

Rat IgG2b-R-PE-Cy5.5 conjugate (isotype control)

20005-13-PC5 25 tests
EUR 213.00

Rat IgG2b-R-PE conjugate (isotype control)

20005-13-PE 25 tests
EUR 202.00

Rat IgG2c-Biotin conjugate (isotype control)

20005-14-B 100 ug
EUR 225.00

Rat IgG2c-FITC conjugate (isotype control)

20005-14-F 100 ug
EUR 225.00

Rat IgG2c-HRP conjugate (isotype control)

20005-14-HP 100 ug
EUR 225.00

Rat IgG2c-R-PE conjugate (isotype control)

20005-14-PE 50 tests
EUR 250.00

Rat IgG2c unonjugated (isotype control)

20005-14-UL 100 ug
EUR 164.00

Rat IgM (non-immune), purified (isotype control)

20005-2-1 0.1 mg
EUR 164.00

Rat IgM-Biotin conjugate (isotype control)

20005-21-B 100 ug
EUR 225.00

Rat IgM-FITC conjugate (isotype control)

20005-21-F 100 ug
EUR 225.00

Rat IgM-HRP conjugate (isotype control)

20005-21-HP 100 ug
EUR 225.00

Rat IgM-R-PE conjugate (isotype control)

20005-21-PE 25 tests
EUR 202.00

Rat IgA (non-immune), purified (isotype control)

20005-3-1 25 ug
EUR 225.00

Rat IgG, purified (Isotype control)

20005-5 5 mg
EUR 286.00

Rat IgG-Agarose conjugate(aff matrix)

20005-AS-1 0.5 ml
EUR 164.00

Rat IgG-Biotin conjugate (isotype control) (Isotype control)

20005-B 100 ug
EUR 164.00

Rat IgG-FITC conjugate (isotype control) (Isotype control)

20005-F 100 ug
EUR 164.00

Rat IgG-HRP conjugate (isotype control) (Isotype control)

20005-HP 100 ug
EUR 164.00

Rat IgG-PE conjugate (isotype control) (Isotype control)

20005-PE 25 tests
EUR 202.00

FluoroQuest™ Fluorescence Signal Enhancing Solution

20006 5 mL
EUR 132.00
  • R-phrase: R20, R21, R68
  • H-Phrase: H303, H313, H340
  • Symbol for dangerous compounds: T
  • UNSPEC Code: 12352200

Sheep IgG, purified (isotype control)

20006-1 1 mg
EUR 141.00

Sheep IgG-Biotin Conjugate (isotype control, non-immune), purified

20006-1-B 0.5 mg
EUR 202.00

Sheep IgG-FITC Conjugate (isotype control, non-immune), purified

20006-1-F 0.5 mg
EUR 202.00

Sheep IgG-HRP Conjugate (isotype control, non-immune), purified

20006-1-HP 0.5 mg
EUR 202.00

Sheep IgM purified (isotype control)

20006-2 1 mg
EUR 347.00

Sheep IgM-Biotin Conjugate (non-immune) control, purified

20006-2-B 0.1 mg
EUR 225.00

Sheep IgA purified (isotype control)

20006-3 100 ug
EUR 286.00

Sheep IgG Fc-Biotin Conjugate (isotype control, non-immune), purified

20006-4-B 0.5 mg
EUR 202.00

Sheep IgG Fc-FITC Conjugate (isotype control, non-immune), purified

20006-4-F 0.5 mg
EUR 202.00

Sheep IgG Fc-HRP Conjugate (isotype control, non-immune), purified

20006-4-HP 0.5 mg
EUR 202.00

Sheep IgG Fc unlabeled (isotype control, non-immune), purified

20006-4-UL 0.5 mg
EUR 202.00

Human IgG, purified (serum, non-immune, isotype control)

20007-1-1 1 mg
EUR 141.00

Human IgG, purified (serum, non-immune, isotype control)

20007-1-100 100 mg
EUR 895.00

Human IgG, purified (serum, non-immune, isotype control)

20007-1-25 25 mg
EUR 651.00

Human IgG, purified (serum, non-immune, isotype control)

20007-1-5 5 mg
EUR 286.00

Human IgG-Biotin conjugate (isotype control, non-immune), purified

20007-1-B 0.5 mg
EUR 225.00

Human IgG (>98%, non-immune, control, Liquid @ 10 mg/ml, azide free, bulk size)

20007-1-BL-1 10 ml Ask for price

Human IgG (>98%, non-immune, control, powder, azide free, bulk size)

20007-1-BP-1 1 g
EUR 651.00

Human IgG (>98%, non-immune, control, powder, azide free, bulk size)

20007-1-BP-10 10 g
EUR 4313.00

Human IgG-FITC conjugate (isotype control, non-immune), purified

20007-1-F 0.5 mg
EUR 225.00

Human IgG Fab fragment, purified

20007-1-FAB 1 mg
EUR 202.00

Human IgG Fab fragment-Biotin Conjugate, purified

20007-1-FAB-B 0.1 mg
EUR 202.00

Human IgG Fab fragment-FITC Conjugate, purified

20007-1-FAB-F 0.1 mg
EUR 202.00

Human IgG Fab fragment-HRP Conjugate, purified

20007-1-FAB-HP 0.1 mg
EUR 202.00

Human IgG F(ab')2 fragment, purified

20007-1-FAB2 1 mg
EUR 202.00

Human IgG Fab2 fragment-Biotin Conjugate, purified

20007-1-FAB2-B 0.1 mg
EUR 202.00

Human IgG Fab2 fragment-FITC Conjugate, purified

20007-1-FAB2-F 0.1 mg
EUR 202.00

Human IgG Fab2 fragment-HRP Conjugate, purified

20007-1-FAB2-HP 0.1 mg
EUR 202.00

Human IgG (Fc) fragment, purified

20007-1-FC 0.5 mg
EUR 208.00

Human IgG Fc-Biotin conjugate (isotype control, non-immune), purified

20007-1-Fc-B 0.1 mg
EUR 164.00

Human IgG Fc-FITC conjugate (isotype control, non-immune), purified

20007-1-Fc-F 0.1 mg
EUR 164.00

Human IgG Fc-HRP conjugate (isotype control, non-immune), purified

20007-1-Fc-HP 0.1 mg
EUR 164.00

Human IgG (Fc) fragment, purified (>95%, low endotoxin)

20007-1-FC-LE 100 ul
EUR 225.00

Human IgG (Fc) fragment-Biotin purified (>95%, low endotoxin)

20007-1-FC-LE-B 25 ug
EUR 286.00

Human IgG-HRP Conjugate (isotype control)

20007-1-HP 500 ug
EUR 202.00

Human IgG (serum origin, purified >97%, low endotoxin, azide free)

20007-1-LE-1 1 mg
EUR 164.00

Human IgG-Biotin (serum origin, purified >97%, low endotoxin, azide free)

20007-1-LE-BTN 100 ug
EUR 286.00

TruStrip RDT Human IgG Rapid test cards, 10/pk

20007-1-RDT 1 Pk
EUR 171.00

TruStrip RDT Human IgG Rapid test cards, 25/pk

20007-1-RDT-25 1 Pk
EUR 293.00

Human IgM, purified (native, isotype control, >96% pure, ELISA Grade)

20007-2 1 mg
EUR 164.00

Human IgM purified (isotype control, >96% pure, ELISA Grade)

20007-2-10 10 mg
EUR 895.00

Human IgM purified (isotype control, >96% pure, ELISA Grade)

20007-2-5 5 mg
EUR 529.00

Human IgM (myeloma, >96%, non-immune, control; bulk size)

20007-2-B-100 100 mg Ask for price

Human IgM (myeloma, >96%, non-immune, control; bulk size)

20007-2-B-1000 1000 mg Ask for price

Human IgM Fc5u fragment, purified (isotype control)

20007-2-FC5M 100 ug
EUR 164.00

Human IgM, Myeloma Plasma (isotype control)

20007-2-M 1 mg
EUR 225.00

Human IgM-Biotin conjugate (myeloma, isotype control)

20007-2-MB 100 ug
EUR 164.00

Human IgM-FITC conjugate (myeloma, isotype control)

20007-2-MF 100 ug
EUR 164.00

Human IgM-HRP conjugate (myeloma, isotype control)

20007-2-MP 100 ug
EUR 164.00

Human IgM-Rhodamine conjugate (myeloma, isotype control)

20007-2-MR 100 ug
EUR 164.00

Human IgM-Texas Red conjugate (isotype control)

20007-2-MT 100 ug
EUR 164.00

Human IgM, mu Chain, Human Plasma, native (isotype control)

20007-2-MU 100 ug
EUR 164.00

Human IgM (Rheumatoid Factor plasma, >40,000 IU/ml, purifed for ELISA)

20007-2-RF 100 ul
EUR 469.00

Human IgE (myeloma, Kappa), purified (isotype control)

20007-3-100 100 ug
EUR 408.00

Human IgE (myeloma, Kappa), purified (isotype control)

20007-3-1000 1000 ug
EUR 2973.00

Human IgE (myeloma, kappa), purified (isotype control, >95%, low endotoxin, azide free)

20007-3-LE-50 100 ug
EUR 408.00

Human IgE-Biotin (myeloma, kappa), purified (isotype control, >95%, low endotoxin, azide free)

20007-3-LE-BTN 100 ul
EUR 408.00

Human IgE (myeloma, lambda), purified (isotype control)

20007-3L-100 100 ug
EUR 408.00

Human IgE (myeloma, lambda), purified (isotype control)

20007-3L-1000 1000 ug
EUR 2973.00

Human IgE (Native, Plasma), purified (isotype control)

20007-3P 50 ug
EUR 408.00

Human IgM Fab mu fragment (myeloma), purified (isotype control)

20007-4 1 mg
EUR 225.00

Human IgM Fab mu fragment (myeloma)-Biotin conjugate (isotype control)

20007-4-B 100 ug
EUR 225.00

Human IgM Fab mu fragment (myeloma)-FITC conjugate (isotype control)

20007-4-F 100 ug
EUR 225.00

Human IgM Fab mu fragment (myeloma)-HRP conjugate (isotype control)

20007-4-HP 100 ug
EUR 225.00

Human IgM Fab mu fragment (myeloma)-Rhodamine conjugate (isotype control)

20007-4-R 100 ug
EUR 225.00

Human IgM Fab mu fragment (myeloma)-Texas Red conjugate (isotype control)

20007-4-T 100 ug
EUR 225.00

Human IgA purified (native, Plasma) (isotype control)

20007-5-1 1 mg
EUR 164.00

Human IgA purified (native, Plasma) (isotype control)

20007-5-5 5 mg
EUR 590.00

Human IgA1 (myeloma) purified (isotype control)

20007-6-100 100 ug
EUR 164.00

Human IgA1 (myeloma) purified (isotype control)

20007-6-500 500 ug
EUR 469.00

Human IgA2 (myeloma) purified (isotype control)

20007-7-100 100 ug
EUR 164.00

Human IgA2 (myeloma) purified (isotype control)

20007-7-500 500 ug
EUR 469.00

Human IgD, Myeloma Plasma (isotype control)

20007-8-50 50 ug
EUR 286.00

Human IgD, Human Native Plasma (isotype control)

20007-8P-25 25 ug
EUR 286.00

Human IgG-Fc fragment (97%, low endotoxin, azide free)

20007-F-LE-100 100 ug
EUR 164.00

Human IgG-Fc fragment-Biotin (97%, low endotoxin, azide free)

20007-F-LE-BTN 100 ug
EUR 286.00

Human IgG-Fc fragment purified (isotype control)

20007-F100 100 ug
EUR 141.00

Human IgG-Fc fragment purified (isotype control)

20007-F1000 1 mg
EUR 347.00

Human IgG1, Myeloma Plasma

20007-G1-1 1 mg
EUR 202.00

Human IgG1-Biotin Conjugate (-ve control)

20007-G1-B 100 ug
EUR 164.00

Human IgG1-FITC Conjugate (-ve control)

20007-G1-F 100 ug
EUR 164.00

Human IgG1 Fab fragment (myeloma)

20007-G1-Fab 100 ug
EUR 225.00

Recombinant (HEK) Human IgG1 Fc (103Cys/Ser, 99-330aa, His-tag, >95%, low endotoxin)

20007-G1-FC 50 ug
EUR 286.00

Human IgG1-HRP Conjugate (-ve control)

20007-G1-H 100 ug
EUR 164.00

Human IgG1-R-PE Conjugate (-ve control)

20007-G1-PE 100 tests
EUR 225.00

Human IgG2, Myeloma Plasma

20007-G2-1 1 mg
EUR 202.00

Human IgG2-Biotin Conjugate

20007-G2-B 100 ug
EUR 164.00

Human IgG2-FITC Conjugate

20007-G2-F 100 ug
EUR 164.00

Recombinant (HEK) Human IgG2-Fc (257Ser/Ala, 99-327aa, His-tag, >95%, low endotoxin)

20007-G2-FC 50 ug
EUR 286.00

Human IgG2-HRP Conjugate (-ve control)

20007-G2-H 100 ug
EUR 164.00

Human IgG3, Myeloma Plasma

20007-G3-1 1 mg
EUR 408.00

Human IgG3, Native Plasma

20007-G3-1P 100 ug
EUR 347.00

Familial dilated cardiomyopathy brought on by a novel variant within the Lamin A/C gene: a case report

Background: Familial dilated cardiomyopathy (FDCM) is mostly inherited as an autosomal dominant trait. The Lamin A/C (LMNA) gene variants have been recognized to be related to DCM, conductive system problems, kind 2 Emery-Dreifuss muscular dystrophy and a number of other different problems. Right here, we reported a novel variant within the LMNA gene that is likely to be associated to FDCM.

 

Case presentation: A 30-year-old younger man was hospitalized for chest tightness, excessive fatigue, palpitation and impaired exercise tolerance. He had scientific traits together with cardiac dilatation, atrial tachyarrhythmia, extreme conductive system problems, and dyskinesia of each higher limbs and the neck. Genetic sequence evaluation indicated that the affected person carried a novel c.1325 T>C heterozygous LMNA gene variant. Catheter ablation and cardiac resynchronization remedy with pacing perform (CRT-P) have been carried out to deal with the arrhythmia.

 

Conclusion: The variant c.1325 T>C is a novel variant within the LMNA gene that has not been beforehand reported. Younger sufferers with DCM, conductive system problems and skeletal myopathy ought to be alert to the potential for LMNA gene variant. Cardiac resynchronization remedy (CRT) could also be an affordable selection for affected person carrying a LMNA gene variant with third-degree atrioventricular block even when the left ventricular ejection fraction is preserved with the intention to stop the deterioration of cardiac perform brought on by proper ventricular pacing dependency.

 

Genetic evaluation of kids with congenital ocular anomalies in three ecological areas of Nepal: a section II of Nepal pediatric ocular illnesses research

 

Background: Genetic eye illnesses represent a big and heterogeneous group of childhood ocular morbidity. Particular person illnesses could trigger a number of structural anomalies and developmental options. Nepal Pediatric Ocular Illness Research (NPODS) was a population-based epidemiological research carried out throughout three ecological areas of Nepal to find out the prevalence and etiology of childhood ocular morbidity and blindness. In Part II of this research, genetic evaluation was carried out for kids who have been discovered to have congenital ocular anomalies.

 

Methodology: It was a cross sectional descriptive research. A complete of 10,270 youngsters throughout three totally different ecological areas in Nepal (Low lands, hills, and mountains) underwent ocular examinations in NPODS. Out of 374 (3.6%) of kids with ocular abnormalities, 30 have been considered congenital in nature. Focused genetic evaluation, together with genotyping for genes particular to presenting phenotype, was carried out for 25 youngsters utilizing serum samples.

 

Outcomes: Out of 25 youngsters, 18 had significant genetic outcomes. Evaluation revealed one missense alteration G12411T of Zinc Finger Homeobox 4 (ZFHX4) gene in a single participant amongst 10 with congenital ptosis and one other missense variation T > C P. Y374 C of Signaling Receptor and Transporter Retinol 6 (STRA6) gene in a single participant amongst Three with microphthalmos.

 

Conclusion: The research is first of its sort from Nepal and mutant genes have been distinctive to Nepalese Inhabitants. Additional evaluation of genetic components is essential to higher perceive genetic affiliation with ocular illnesses and situations. This helps additional in genetic counseling and doubtless gene remedy to forestall blindness from these situations.

 

Doxorubicin (hydrochloride)

HY-15142 100mg
EUR 147.00

Doxorubicin hydrochloride

GA4969-100MG 100 mg
EUR 181.00

Doxorubicin hydrochloride

GA4969-10MG 10 mg
EUR 78.00

Doxorubicin hydrochloride

GA4969-25MG 25 mg
EUR 98.00

Doxorubicin hydrochloride

GA4969-50MG 50 mg
EUR 126.00

Doxorubicin Hydrochloride

20-abx076623
  • EUR 342.00
  • EUR 787.00
  • 0
  • 1
  • Shipped within 5-12 working days.

Doxorubicin hydrochloride

TNC00267 20mg Ask for price

Doxorubicin hydrochloride USP

D005-10MG 10 mg
EUR 166.00

Doxorubicin hydrochloride USP

D005-25MG 25 mg
EUR 301.00

Doxorubicin Hydrochloride (Autophagy inducer)

SIH-390-10MG 10 mg
EUR 193.00
  • Doxorubicin Hydrochloride is used in a clinical setting for the treatment of a wide range of cancers, including lymphomas, leukemias, and solid tumors of the breast, pancreas, stomach, bladder, and ovaries. This drug intercalates into DNA and therefo
  • Show more
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM)..

Doxorubicin Hydrochloride (Autophagy inducer)

SIH-390-50MG 50 mg
EUR 529.00
  • Doxorubicin Hydrochloride is used in a clinical setting for the treatment of a wide range of cancers, including lymphomas, leukemias, and solid tumors of the breast, pancreas, stomach, bladder, and ovaries. This drug intercalates into DNA and therefo
  • Show more
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM)..

Erlotinib, Hydrochloride Salt

1588-100
EUR 169.00

Erlotinib, Hydrochloride Salt

1588-1000
EUR 398.00

Doxorubicin

ADC-P-013 unit Ask for price

Doxorubicin

HY-15142A 100mg
EUR 215.00

Doxorubicin

abx188695-1g 1 g
EUR 467.00
  • Shipped within 1-2 weeks.

Doxorubicin

A3966-10 10 mg
EUR 108.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin

A3966-100 100 mg
EUR 235.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin

A3966-25 25 mg
EUR 131.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin

A3966-5.1 10 mM (in 1mL DMSO)
EUR 131.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin

A3966-S Evaluation Sample
EUR 81.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin

D063-100MG 100 mg
EUR 1051.00

Doxorubicin

D063-25MG 25 mg
EUR 322.00

Erlotinib, Hydrochloride Salt, >99%

BC026-101 1g
EUR 273.00

Erlotinib, Hydrochloride Salt, >99%

BC026-102 2g
EUR 388.00

Erlotinib, Hydrochloride Salt, >99%

BC026-105 5g
EUR 570.00

Adriamycin (Doxorubicin)

E1KS1208 10mg
EUR 409.00

Doxorubicin HCl

20-abx184016
  • EUR 746.00
  • EUR 1483.00
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  • Shipped within 1-2 weeks.

Doxorubicin 10mM

TG4120 0.25ml
EUR 156.00

17-DMAG, Hydrochloride Salt, >98%

BC024-001 1mg
EUR 178.00

17-DMAG, Hydrochloride Salt, >98%

BC024-005 5mg
EUR 286.00

17-DMAG, Hydrochloride Salt, >98%

BC024-010 10mg
EUR 408.00

17-DMAG, Hydrochloride Salt, >98%

BC024-025 25mg Ask for price

17-DMAG, Hydrochloride Salt, >99%

BC024-100 100mg Ask for price

17-DMAG, Hydrochloride Salt, >99%

BC024-101 1g Ask for price

17-DMAG, Hydrochloride Salt, >99%

BC024-250 250mg Ask for price

OSU-03012, Hydrochloride Salt, >98%

BC061-005 5mg
EUR 313.00

OSU-03012, Hydrochloride Salt, >98%

BC061-025 25mg
EUR 529.00

Doxorubicin (Adriamycin) HCl

A1832-10 10 mg
EUR 125.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin (Adriamycin) HCl

A1832-100 100 mg
EUR 467.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin (Adriamycin) HCl

A1832-25 25 mg
EUR 189.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin (Adriamycin) HCl

A1832-5.1 10 mM (in 1mL DMSO)
EUR 113.00
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas.

Doxorubicin HCl, 100mg

R2531-100mg
EUR 1300.00

Doxorubicin HCl, 10mg

R2531-10mg
EUR 197.00

Anti-EGFR-doxorubicin ADC

ADC-W-600 1mg Ask for price
Description: This ADC product is comprised of an anti-EGFR monoclonal antibody conjugated via a linker to a doxorubicin

Anti-CD22-DIBO-doxorubicin ADC

ADC-W-339 1mg Ask for price
Description: This ADC product is comprised of an anti-CD22 monoclonal antibody conjugated via a DIBO linker to a doxorubicin

Anti-TNFRSF8 (cAC10)-DIBO-doxorubicin ADC

ADC-W-406 1mg Ask for price
Description: This ADC product is comprised of an anti-TNFRSF8 monoclonal antibody (cAC10) conjugated via a DIBO linker to a doxorubicin

Anti-ERBB2 (Trastuzumab)-NGM-doxorubicin ADC

ADC-W-412 1mg Ask for price
Description: This ADC product is comprised of an anti-ERBB2 monoclonal antibody conjugated via a NGM linker to adoxorubicin

Anti-EGFR (cetuximab)-SMCC-Doxorubicin ADC

ADC-W-504 1mg Ask for price
Description: This ADC product is comprised of an anti-EGFR monoclonal antibody (cetuximab) conjugated via a SMCC linker to Doxorubicin

Anti-EpCAM (MOC31)-hydrazone-Doxorubicin ADC

ADC-W-581 1mg Ask for price
Description: This ADC product is comprised of an anti-EPCAM monoclonal antibody (MOC31) conjugated via a hydrazone linker to Doxorubicin

Anti-FUT3 (clone cBR96)-hydrazone-doxorubicin ADC

ADC-W-423 1mg Ask for price
Description: This ADC product is comprised of an anti-FUT3 monoclonal antibody (clone cBR96) conjugated via a hydrazone linker to adoxorubicin

Anti-CD70 (clone h1F6)-β-glucuronide-doxorubicin ADC

ADC-W-376 1mg Ask for price
Description: This ADC product is comprised of an anti-CD70 monoclonal antibody (clone h1F6) conjugated via a β-glucuronide linker to a doxorubicin

Bile salt

BB0225 25g
EUR 79.58
  • Product category: Biochemicals/Detergents/Surfactants

Anti-TNFRSF8 (cCA10)-β-glucuronide-doxorubicin propyloxazoline (DPO) ADC

ADC-W-353 1mg Ask for price
Description: This ADC product is comprised of an anti-TNFRSF8 monoclonal antibody (cCA10) conjugated via a β-glucuronide linker to a doxorubicin propyloxazoline (DPO)

Human HeLa (Cervix Adenocarcinoma) Cell Nuclear Extract - Doxorubicin Stimulated

HCL-2004 100ug
EUR 225.00

Human HeLa (Cervix Adenocarcinoma) Whole Cell Lysate - Doxorubicin Stimulated

HCL-2010 100ug
EUR 213.00

Stachydrine (hydrochloride)

C3648-100 100 mg
EUR 119.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)

C3648-1000 1 g
EUR 467.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)

C3648-250 250 mg
EUR 206.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)

C3648-500 500 mg
EUR 328.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Barnidipine (hydrochloride)

C3727-100 100 mg
EUR 203.00
Description: Barnidipine is a calcium-channel blocker.A calcium channel, an ion channel which displays selective permeability to calcium ions, is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.

Barnidipine (hydrochloride)

C3727-50 50 mg
EUR 155.00
Description: Barnidipine is a calcium-channel blocker.A calcium channel, an ion channel which displays selective permeability to calcium ions, is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.

MS049 (hydrochloride)

C3776-10 10 mg
EUR 200.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-100 100 mg
EUR 1181.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-25 25 mg
EUR 382.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-5 5 mg
EUR 139.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-5.1 10 mM (in 1mL DMSO)
EUR 150.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)

C3776-50 50 mg
EUR 653.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

Guanabenz (hydrochloride)

C3786-100 100 mg
EUR 231.00
Description: Guanabenz is an orally active ?2-adrenoceptor agonist with hypotensive effects [1]. The ?2 adrenergic receptors belong to a family of G protein-coupled receptor (GPCR), mediate many physiological actions of the endogenous catecholamines adrenaline and noradrenaline.

Guanabenz (hydrochloride)

C3786-50 50 mg
EUR 144.00
Description: Guanabenz is an orally active ?2-adrenoceptor agonist with hypotensive effects [1]. The ?2 adrenergic receptors belong to a family of G protein-coupled receptor (GPCR), mediate many physiological actions of the endogenous catecholamines adrenaline and noradrenaline.

Ulixertinib (hydrochloride)

C3921-10 10 mg
EUR 406.00
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Ulixertinib (hydrochloride)

C3921-25 25 mg
EUR 661.00
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Ulixertinib (hydrochloride)

C3921-5 5 mg
EUR 250.00
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Chlorcyclizine (hydrochloride)

C3989-100 100 mg
EUR 118.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)

C3989-1000 1 g
EUR 595.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)

C3989-250 250 mg
EUR 210.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)

C3989-500 500 mg
EUR 357.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Lofexidine (hydrochloride)

C3990-1000 1 g
EUR 126.00
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Lofexidine (hydrochloride)

C3990-5.1 10 mM (in 1mL H2O)
EUR 113.00
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Lofexidine (hydrochloride)

C3990-500 500 mg
EUR 100.00
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Nortriptyline (hydrochloride)

C4077-100 100 mg
EUR 163.00
Description: Ki: 3.4 nM: blocks the norepinephrine transporter.Ki: 161 nM: inhibits the serotonin transporter.

Nortriptyline (hydrochloride)

C4077-5.1 10 mM (in 1mL DMSO)
EUR 113.00
Description: Ki: 3.4 nM: blocks the norepinephrine transporter.Ki: 161 nM: inhibits the serotonin transporter.

Nortriptyline (hydrochloride)

C4077-50 50 mg
EUR 116.00
Description: Ki: 3.4 nM: blocks the norepinephrine transporter.Ki: 161 nM: inhibits the serotonin transporter.

Imipramine (hydrochloride)

C4117-5.1 10 mM (in 1mL H2O)
EUR 113.00
Description: Imipramine (hydrochloride) is a tricyclic antidepressant and is mainly used in the treatment of major depression and enuresis [1]. Antidepressants are antagonists of many neurotransmitter receptors in human brain [3].

Imipramine (hydrochloride)

C4117-5000 5 g
EUR 108.00
Description: Imipramine (hydrochloride) is a tricyclic antidepressant and is mainly used in the treatment of major depression and enuresis [1]. Antidepressants are antagonists of many neurotransmitter receptors in human brain [3].

Clorgyline (hydrochloride)

C4137-100 100 mg
EUR 224.00
Description: Clorgyline (hydrochloride) is an irreversible, potent and selective monoamine oxidase (MAO) A inhibitor with Ki values of 0.054 and 58 ?M and IC50 values of 0.0012 and 1.9 ?M for MAO-A and MAO-B, respectively [1][2].

Clorgyline (hydrochloride)

C4137-25 25 mg
EUR 110.00
Description: Clorgyline (hydrochloride) is an irreversible, potent and selective monoamine oxidase (MAO) A inhibitor with Ki values of 0.054 and 58 ?M and IC50 values of 0.0012 and 1.9 ?M for MAO-A and MAO-B, respectively [1][2].

Clorgyline (hydrochloride)

C4137-50 50 mg
EUR 154.00
Description: Clorgyline (hydrochloride) is an irreversible, potent and selective monoamine oxidase (MAO) A inhibitor with Ki values of 0.054 and 58 ?M and IC50 values of 0.0012 and 1.9 ?M for MAO-A and MAO-B, respectively [1][2].

Doxepin (hydrochloride)

C4153-5.1 10 mM (in 1mL DMSO)
EUR 113.00
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine.

Doxepin (hydrochloride)

C4153-5000 5 g
EUR 168.00
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine.

Anhydrochlortetracycline (hydrochloride)

C4218-1 1 mg
EUR 132.00
Description: Anhydrochlortetracycline was produced by the acid degradation of chlortetracycline. Anhydrochlortetracycline only have a fraction of the antibacterial activity of chlortetracycline. Anhydrochlortetracycline strongly inhibited the growth of Streptomyces aureofaciem.

Anhydrochlortetracycline (hydrochloride)

C4218-5 5 mg
EUR 255.00
Description: Anhydrochlortetracycline was produced by the acid degradation of chlortetracycline. Anhydrochlortetracycline only have a fraction of the antibacterial activity of chlortetracycline. Anhydrochlortetracycline strongly inhibited the growth of Streptomyces aureofaciem.

Anhydrotetracycline (hydrochloride)

C4291-100 100 mg
EUR 241.00
Description: Anhydrotetracycline (hydrochloride) (ATC) is a powerful effector for the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) systems [1].

Anhydrotetracycline (hydrochloride)

C4291-25 25 mg
EUR 123.00
Description: Anhydrotetracycline (hydrochloride) (ATC) is a powerful effector for the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) systems [1].

Anhydrotetracycline (hydrochloride)

C4291-50 50 mg
EUR 171.00
Description: Anhydrotetracycline (hydrochloride) (ATC) is a powerful effector for the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) systems [1].

(±)-Salsolinol (hydrochloride)

C4364-500 500 mg
EUR 308.00
Description: (±)-Salsolinol targets depolarize dopamineric neurons. Dopaminergic neurons produce dopamine, a neurotransmitter with various roles in neurological functions.

Midodrine (hydrochloride)

C4493-100 100 mg
EUR 113.00
Description: Ki: 2, 6.9, and 1.7 ?M for ?1A, ?1B, ?1D, respectivelyMidodrine is the prodrug of the ?1-adrenergic receptor agonist, 1-(2?,5?-dimethoxyphenyl)-2-aminoethanol.

Midodrine (hydrochloride)

C4493-250 250 mg
EUR 200.00
Description: Ki: 2, 6.9, and 1.7 ?M for ?1A, ?1B, ?1D, respectivelyMidodrine is the prodrug of the ?1-adrenergic receptor agonist, 1-(2?,5?-dimethoxyphenyl)-2-aminoethanol.

Celiprolol (hydrochloride)

C4521-10 10 mg
EUR 254.00
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Celiprolol (hydrochloride)

C4521-25 25 mg
EUR 500.00
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Celiprolol (hydrochloride)

C4521-5 5 mg
EUR 183.00
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Aceclidine (hydrochloride)

C4635-1000 1 g
EUR 328.00

Aceclidine (hydrochloride)

C4635-500 500 mg
EUR 206.00

Trimidox (hydrochloride)

C4714-10 10 mg
EUR 184.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Trimidox (hydrochloride)

C4714-25 25 mg
EUR 370.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Trimidox (hydrochloride)

C4714-5 5 mg
EUR 121.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Trimidox (hydrochloride)

C4714-50 50 mg
EUR 618.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Cycloguanil (hydrochloride)

C5763-10 10 mg
EUR 109.00
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Cycloguanil (hydrochloride)

C5763-25 25 mg
EUR 163.00
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Cycloguanil (hydrochloride)

C5763-50 50 mg
EUR 206.00
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

VU590 (hydrochloride)

C4778-10 10 mg
EUR 195.00

VU590 (hydrochloride)

C4778-25 25 mg
EUR 389.00

VU590 (hydrochloride)

C4778-5 5 mg
EUR 139.00

Bufuralol (hydrochloride)

C5043-1 1 mg
EUR 139.00
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

Bufuralol (hydrochloride)

C5043-10 10 mg
EUR 628.00
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

Bufuralol (hydrochloride)

C5043-5 5 mg
EUR 457.00
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

AN3365 (hydrochloride)

C5068-10 10 mg
EUR 328.00
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

AN3365 (hydrochloride)

C5068-25 25 mg
EUR 659.00
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

AN3365 (hydrochloride)

C5068-5 5 mg
EUR 206.00
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

Calindol (hydrochloride)

C5329-10 10 mg
EUR 440.00
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Calindol (hydrochloride)

C5329-25 25 mg
EUR 902.00
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Calindol (hydrochloride)

C5329-5 5 mg
EUR 270.00
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Kasugamycin (hydrochloride)

C5503-10000 10 g
EUR 350.00
Description: Kasugamycin is an aminoglycosidic antibiotic. Aminoglycoside, a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agent, inhibits protein synthesis and contains as a portion of the molecule an amino-modified glycoside.

Kasugamycin (hydrochloride)

C5503-5000 5 g
EUR 251.00
Description: Kasugamycin is an aminoglycosidic antibiotic. Aminoglycoside, a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agent, inhibits protein synthesis and contains as a portion of the molecule an amino-modified glycoside.

Ciprofloxacin (hydrochloride)

C5539-10000 10 g
EUR 116.00
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Ciprofloxacin (hydrochloride)

C5539-25000 25 g
EUR 154.00
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Ciprofloxacin (hydrochloride)

C5539-50000 50 g
EUR 224.00
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Fendiline (hydrochloride)

C5675-5000 5 g
EUR 122.00
Description: Fendiline is an ?2-adrenergic receptor antagonist and L-type calcium channel blocker [1,2].The ?2 adrenergic receptor is a G protein-coupled receptor (GPCR). Until now, three different ?2-receptor subtypes have been identified: ?2A, ?2B, and ?2C.

Afuresertib hydrochloride

B1848-5
EUR 175.00

Chlorpromazine hydrochloride

B1992-100
EUR 120.00

Chlorpromazine hydrochloride

B1992-500
EUR 294.00

Triflupromazine hydrochloride

B1993-100
EUR 120.00

 ZLN024 hydrochloride

B2034-25
EUR 588.00

 ZLN024 hydrochloride

B2034-5
EUR 185.00

Topotecan hydrochloride

B2050-10
EUR 131.00

Givinostat hydrochloride

B2081-25
EUR 756.00

Givinostat hydrochloride

B2081-5
EUR 229.00

Moexipril hydrochloride

B2134-25
EUR 294.00

Imidapril hydrochloride

B2135-25
EUR 414.00

Imidapril hydrochloride

B2135-5
EUR 142.00

Benazepril hydrochloride

B2138-250
EUR 294.00

Benazepril hydrochloride

B2138-50
EUR 131.00

Dorzolamide hydrochloride

B2185-10
EUR 120.00

Dorzolamide hydrochloride

B2185-50
EUR 327.00

Eltoprazine hydrochloride

B2301-25
EUR 457.00

Eltoprazine hydrochloride

B2301-5
EUR 153.00

Papaverine hydrochloride

B2315-250
EUR 262.00

Papaverine hydrochloride

B2315-50
EUR 120.00

Sarecycline hydrochloride

B2383-25
EUR 588.00

Sarecycline hydrochloride

B2383-5
EUR 185.00

Sertraline (hydrochloride)

B2393-10
EUR 131.00

Sertraline (hydrochloride)

B2393-50
EUR 327.00

Migalastat hydrochloride

B2404-25
EUR 756.00

Migalastat hydrochloride

B2404-5
EUR 229.00

Butenafine hydrochloride

B2421-250
EUR 327.00

Butenafine hydrochloride

B2421-50
EUR 120.00

Naftifine hydrochloride

B2422-10
EUR 131.00

Naftifine hydrochloride

B2422-50
EUR 349.00

Rilpivirine hydrochloride

B2427-25
EUR 414.00

Rilpivirine hydrochloride

B2427-5
EUR 142.00

Tirabrutinib hydrochloride

B2556-25
EUR 457.00

Tirabrutinib hydrochloride

B2556-5
EUR 153.00

Robenidine hydrochloride

B2560-1G
EUR 131.00

Robenidine hydrochloride

B2560-5G
EUR 262.00

Sardomozide Hydrochloride

B2566-25
EUR 631.00

Sardomozide Hydrochloride

B2566-5
EUR 196.00

Riviciclib hydrochloride

B2567-1
EUR 142.00

Riviciclib hydrochloride

B2567-5
EUR 414.00

CPTH2 (hydrochloride)

B2815-1
EUR 120.00

CPTH2 (hydrochloride)

B2815-5
EUR 294.00

Resminostat (hydrochloride)

B2852-25
EUR 588.00

Resminostat (hydrochloride)

B2852-5
EUR 185.00

Almorexant hydrochloride

B3241-10 10 mg
EUR 440.00
Description: Almorexant is an antagonist of Orexin 1 receptor (OX1R) and Orexin 2 receptor (OX2R) with Kd values of 1.3nM and 0.17nM, respectively [1].

Almorexant hydrochloride

B3241-5 5 mg
EUR 270.00
Description: Almorexant is an antagonist of Orexin 1 receptor (OX1R) and Orexin 2 receptor (OX2R) with Kd values of 1.3nM and 0.17nM, respectively [1].

Memantine hydrochloride

B3308-200 200 mg
EUR 137.00
Description: Memantine hydrochloride is an antagonist of NMDA receptor with IC50 values of 0.93?M, 0.82?M and 0.47?M for NRIa/NR2A, NRIa/NR2B and NRIa/NR2D, respectively [1].

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