Next generation sequencing reveals a novel pathogenic variant in the ATMgene
Introduction: Ataxia telangiectasia (A-T) is a uncommon autosomal recessive multisystemic illness. Sufferers with the A-T syndrome current a broad spectrum of illness phenotypes. The ATM (ataxia telangiectasia mutated) gene, the one causative gene for A-T.
Methodology: A affected person of Persian origin presenting with typical A-T was referred to our genetics middle for specialised genetic counseling and testing. Focused next-generation sequencing (NGS) was utilized. Sanger sequencing was used to substantiate the candidate variant. Modeling was carried out utilizing the SWISS-MODEL server.Outcomes: A homozygous stop-gain variant c.829G > T (p.E277*) was discovered within the ATM gene. This variant was confirmed by Sanger sequencing and modeling of native construction and truncated construction was carried out.
Conclusion: Thus far, only a few pathogenic variants of the ATM gene have been reported from the Iranian inhabitants. The discovering has implications in molecular diagnostic for A-T in Iran.

RIPA Lysis Buffer (Strong) |
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abx090624-100ml | Abbexa | 100 ml | EUR 260.4 |
RIPA Lysis Buffer (Strong) |
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HY-K1001 | MedChemExpress | 100 mL | EUR 176.4 |
Pierce Seal Strong Sheets |
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PCR0632 | Scientific Laboratory Supplies | PK100 | EUR 124.8 |
WB Stripping Solution Strong |
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05677-65 | NACALAI TESQUE | 500ML | EUR 142.8 |
Pierce Seal Strong Roll610mX78mm |
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PCR0628 | Scientific Laboratory Supplies | 1ROLL | EUR 981.6 |
PCR Foil Seal Strong Sheets |
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PCR0528 | Scientific Laboratory Supplies | PK100 | EUR 188.4 |
Tweezers Fine Strong CF Tips |
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INS5058 | Scientific Laboratory Supplies | EACH | EUR 33.42 |
Tweezers Flat Strong CF Tips |
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INS5100 | Scientific Laboratory Supplies | EACH | EUR 39.04 |
Pierce Seal Strong Sample Roll |
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PCR0630 | Scientific Laboratory Supplies | 1ROLL | EUR 53.01 |
replacement tip Kit strong thick |
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INS2090 | Scientific Laboratory Supplies | EACH | EUR 10.35 |
replacement tip Kit strong point |
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INS2094 | Scientific Laboratory Supplies | EACH | EUR 10.35 |
replacement tip Kit strong thick |
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INS2058 | Scientific Laboratory Supplies | EACH | EUR 10.35 |
EP Reagent Sodium Hydroxide Sol. Strong |
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1081404 | Scientific Laboratory Supplies | 1L | EUR 170.4 |
EP Reagent Sodium Hypochlorite Sol. Strong |
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10816005 | Scientific Laboratory Supplies | 500ML | EUR 121.2 |
Tweezers, Rubis Sturdy, Strong Pointed, 115mm, 4.5€ |
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25046-1 | Polysciences Europe GmbH | 1EA | EUR 48 |
Genistin |
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1535-10 | Biovision | each | EUR 196.8 |
Genistin |
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N1860-20 | ApexBio | 20 mg | EUR 268.8 |
Description: Actions Inactive analog of genistein; useful as a negative control for genistein and other tyrosine kinase inhibitors. Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT),with no measurable effect on mammalian or microbial DNA p |
Genistin |
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HY-N0595 | MedChemExpress | 50mg | EUR 170.4 |
Genistin |
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GC2802-10 | Glentham Life Sciences | 10 | EUR 242.4 |
Genistin |
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GC2802-100 | Glentham Life Sciences | 100 | EUR 960.1 |
Genistin |
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GC2802-25 | Glentham Life Sciences | 25 | EUR 382.3 |
Genistin |
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GC2802-250 | Glentham Life Sciences | 250 | EUR 1845.7 |
Genistin |
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GC2802-50 | Glentham Life Sciences | 50 | EUR 577.8 |
Genistin |
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TB0370-1000 | ChemNorm | 4X20mg | EUR 321.6 |
Magnetic Base Support Z w/ Strong Magnet - 34.5mm |
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M-R-1013161 | MiTeGen | 1 UNIT | EUR 46 |
Description: Magnetic Base Support Z w/ Strong Magnet - 34.5mm |
Magnetic Base Support Z w/ Strong Magnet - 27.5mm |
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M-R-1015229 | MiTeGen | 1 UNIT | EUR 46 |
Description: Magnetic Base Support Z w/ Strong Magnet - 27.5mm |
Silver Protein for Histology, Strong (not certified) |
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25108-25 | Polysciences Europe GmbH | 25g | EUR 431 |
Description: 9015-51-4 |
Silver Protein for Histology, Strong (not certified) |
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25108-5 | Polysciences Europe GmbH | 5g | EUR 113 |
Description: 9015-51-4 |
UCW5072, Low TOC Strong Base Anion Resin, OH Form |
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50240-1 | Polysciences Europe GmbH | 1000ml | EUR 192 |
UCW5072, Low TOC Strong Base Anion Resin, OH Form |
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50240-250 | Polysciences Europe GmbH | 250ml | EUR 62 |
Genistin, >99% |
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BC034-025 | GenDepot | 25mg | EUR 278.4 |
Genistin, >99% |
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BC034-050 | GenDepot | 50mg | EUR 327.6 |
Genistin, >99% |
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BC034-100 | GenDepot | 100mg | EUR 537.6 |
Genistin(Genistoside) |
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E1KS2301 | EnoGene | 25mg | EUR 390 |
A510, Type 2 Macroporous Strong Base Rsin, Chloride Form |
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50223-1 | Polysciences Europe GmbH | 1000ml | EUR 144 |
Description: 69011-15-0 |
A510, Type 2 Macroporous Strong Base Resin, Chloride Form |
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50223-250 | Polysciences Europe GmbH | 250ml | EUR 47 |
Description: 69011-15-0 |
Genistin malonate |
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TB0588-0005 | ChemNorm | 10mg | EUR 886.8 |
A400, Type 1 Porous Strong Base Anion Resin, Chorlide Form |
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50218-1 | Polysciences Europe GmbH | 1000ml | EUR 144 |
Description: 9052-45-3 |
A400, Type 1 Porous Strong Base Anion Resin, Chorlide Form |
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50218-250 | Polysciences Europe GmbH | 250ml | EUR 47 |
Description: 9052-45-3 |
Optically clear sealing film for qPCR, Strong Bond, for PP plates, 100/pk |
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MS1000-PCR2 | Benchmark Scientific | 1 each | EUR 145 |
Foil seals, strong bonding for cold storage (-200 to 110°C) and DMSO, for PP plates, 100/pk |
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MS1000-F2 | Benchmark Scientific | 1 each | EUR 145 |
Strongzyme Goat anti Mouse IgG (H+L) (HRP) |
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43R-1653 | Fitzgerald | 1 ml | EUR 763.2 |
Description: Strongzyme Goat anti-Mouse IgG (H+L) secondary antibody (HRP) |
Strongzyme Rabbit anti Goat IgG (H+L) (HRP) |
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43R-1650 | Fitzgerald | 1 ml | EUR 940.8 |
Description: Strongzyme Rabbit anti Goat IgG (H + L) (HRP) secondary antibody |
Strongzyme Goat anti Rabbit IgG (H + L) (HRP) |
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43R-1652 | Fitzgerald | 1 ml | EUR 763.2 |
Description: Strongzyme Goat anti Rabbit IgG (H + L) secondary antibody (HRP) |
QPCR Kit DNA Strongylus vulgaris |
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MOL8940 | Scientific Laboratory Supplies | EACH | EUR 1004.01 |
QPCR Kit DNA Strongylus vulgaris |
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MOL8942 | Scientific Laboratory Supplies | EACH | EUR 1274.27 |
Strongyloides (IgG/IgM) ELISA Kit (Human) (OKNA00174) |
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OKNA00174 | Aviva Systems Biology | 96 Wells | EUR 505.2 |
Description: Description of target: Strongyloides is a genus containing some 50 species of obligate gastrointestinal parasites of vertebrates. Strongyloides stercoralis is the scientific name of a human parasitic roundworm causing the disease of strongyloidiasis. Its common name is pinworm in the UK and threadworm in the US. The Strongyloides stercoralis nematode can parasitize humans. The adult parasitic stage lives in tunnels in the mucosa of the small intestine.S. stercoralis can be found in areas with tropical and subtropical climates but cases also occur in temperate area, more frequently in rural areas. S. stercoralis has a very low prevalence in societies where fecal contamination of soil or water is rare. Many people infected are usually asymptomatic at first. Symptoms include dermatitis: swelling, itching, larva currens, and mild hemorrhage at the site where the skin has been penetrated. If the parasite reaches the lungs, the chest may feel as if it is burning, and wheezing and coughing may result, along with pneumonia-like symptoms (Löffler's syndrome). The intestines could eventually be invaded, leading to burning pain, tissue damage, sepsis, and ulcers. In severe cases, edema may result in obstruction of the intestinal tract, as well as loss of peristaltic contractions. Strongyloides infection in immunocompromised individuals (particularly following the administration of steroids, for example following transplant surgery) can result in disseminated strongyloidiasis, in which worms move beyond the confines of the gut into other organs. This is fatal unless antiStrongyloides therapy is given.Locating juvenile larvae, either rhabditiform or filariform, in recent stool samples will confirm the presence of this parasite. Other techniques used include direct fecal smears, culturing fecal samples on agar plates, serodiagnosis through ELISA, and duodenal fumigation.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Reverse Capture Sandwich ELISA ;Sensitivity: Sensitivity is determined as the probability of the assay indicating a positive score in samples with the specific analyte present: 87.9% |
StrongZyme Streptavidin-PolyHRP (High Load) |
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43R-1645 | Fitzgerald | 1 mg | EUR 369.6 |
Description: StrongZyme Streptavidin-PolyHRP conjugate (High Load) |
Strontium Oxide |
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abx186564-500g | Abbexa | 500 g | EUR 309.6 |
Strontium oxide, 99.5% |
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GX8751-50 | Glentham Life Sciences | 50 | EUR 585.6 |
ICP Std Strontium 1000ug/mL in 2-5% HCl |
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PSR2A3 | Scientific Laboratory Supplies | 100ML | EUR 120.12 |
ICP Std Strontium 1000ug/mL in 2-5% HCl |
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PSR2B3 | Scientific Laboratory Supplies | 250ML | EUR 214.12 |
ICP Std Strontium 1000ug/mL in 2-5% HCl |
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PSR2C3 | Scientific Laboratory Supplies | 500ML | EUR 265.04 |
ICP Std Strontium 10000ug/mL in 2-5% HCl |
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PSR4A3 | Scientific Laboratory Supplies | 100ML | EUR 208.9 |
ICP Std Strontium 10000ug/mL in 2-5% HCl |
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PSR4B3 | Scientific Laboratory Supplies | 250ML | EUR 352.51 |
Strontium bromide, 99.99% |
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GX4255-10 | Glentham Life Sciences | 10 | EUR 325.9 |
Strontium nitrate, 99.999% |
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GX6363-50 | Glentham Life Sciences | 50 | EUR 391 |
Strontium nitrate, 99.99% |
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GX1574-50 | Glentham Life Sciences | 50 | EUR 280.7 |
Strontium chloride |
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B7708-50 | ApexBio | 50 mg | EUR 154.8 |
Strontium Ranelate |
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A8526-10 | ApexBio | 10 mg | EUR 397.2 |
Description: Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic. |
ICP Std Strontium 100ug/mL in 2-5% HNO3 |
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PSR1A2 | Scientific Laboratory Supplies | 100ML | EUR 117.5 |
ICP Std Strontium 1000ug/mL in 2-5% HNO3 |
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PSR2B2 | Scientific Laboratory Supplies | 250ML | EUR 214.12 |
ICP Std Strontium 1000ug/mL in 2-5% HNO3 |
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PSR2C2 | Scientific Laboratory Supplies | 500ML | EUR 261.6 |
ICP Std Strontium 10000ug/mL in 2-5% HNO3 |
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PSR4A2 | Scientific Laboratory Supplies | 100ML | EUR 208.9 |
ICP Std Strontium 10000ug/mL in 2-5% HNO3 |
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PSR4B2 | Scientific Laboratory Supplies | 250ML | EUR 355.12 |
ICP Std Strontium 10000ug/mL in 3.5% HNO3 |
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PSR4B4-500ML | Scientific Laboratory Supplies | 500ML | EUR 671.08 |
Strontium Ranelate |
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HY-17397 | MedChemExpress | 500mg | EUR 820.8 |
Strontium titanate, 99.9% |
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GX4862-100 | Glentham Life Sciences | 100 | EUR 340.5 |
Strontium titanate, 99.9% |
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GX4862-25 | Glentham Life Sciences | 25 | EUR 164.5 |
Strontium fluoride, 99.99% |
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GX7221-10 | Glentham Life Sciences | 10 | EUR 134.1 |
Strontium fluoride, 99.99% |
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GX7221-25 | Glentham Life Sciences | 25 | EUR 286.8 |
Strontium fluoride, 99.99% |
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GX7221-50 | Glentham Life Sciences | 50 | EUR 562.1 |
Strontium fluoride, 99.9% |
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GX8262-10 | Glentham Life Sciences | 10 | EUR 116.1 |
Strontium fluoride, 99.9% |
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GX8262-50 | Glentham Life Sciences | 50 | EUR 280.2 |
Strontium fluoride, 99% |
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GX3818-250 | Glentham Life Sciences | 250 | EUR 137.2 |
Strontium titanate, 99+% |
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GX1727-250 | Glentham Life Sciences | 250 | EUR 108.5 |
Strontium Ranelate |
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A8526-100 | ApexBio | 100mg | EUR 126 |
Description: Calcium Channel activator |
Strontium Ranelate |
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A8526-500 | ApexBio | 500mg | EUR 437 |
Description: Calcium Channel activator |
AAS Strontium Std 1000ppm in 0.5M HNO3 |
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AASRH | Scientific Laboratory Supplies | 500ML | EUR 246 |
AAS Strontium Std 10000ppm in 1M HNO3 |
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AASRM | Scientific Laboratory Supplies | 500ML | EUR 356.4 |
Flame Std Strontium 1000ppm |
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FISR1 | Scientific Laboratory Supplies | 500ML | EUR 190.8 |
Strontium aluminate, 99+% |
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GX5543-10 | Glentham Life Sciences | 10 | EUR 113.1 |
Strontium aluminate, 99+% |
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GX5543-50 | Glentham Life Sciences | 50 | EUR 262.3 |
Strontium carbonate, 99.999% |
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GX5614-25 | Glentham Life Sciences | 25 | EUR 258.5 |
Strontium zirconate, 99+% |
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GX8495-250 | Glentham Life Sciences | 250 | EUR 120.5 |
Strontium carbonate, 99+% |
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GX9308-100 | Glentham Life Sciences | 100 | EUR 129.6 |
Strontium carbonate, 99+% |
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GX9308-250 | Glentham Life Sciences | 250 | EUR 229.6 |
Strontium molybdate, 99.9% |
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GX0022-50 | Glentham Life Sciences | 50 | EUR 189 |
Strontium tungstate, 99.9% |
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GX0472-10 | Glentham Life Sciences | 10 | EUR 101 |
Strontium tungstate, 99.9% |
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GX0472-50 | Glentham Life Sciences | 50 | EUR 233 |
Strontium carbonate |
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GK8492-1 | Glentham Life Sciences | 1 | EUR 50.3 |
Strontium carbonate |
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GK8492-250 | Glentham Life Sciences | 250 | EUR 25.5 |
Strontium carbonate |
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GK8492-5 | Glentham Life Sciences | 5 | EUR 176.1 |
ICP Standard Strontium 2-5pc |
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PSR2A2 | Scientific Laboratory Supplies | 100ML | EUR 221.95 |
IC Cation Std Strontium 200ppm in H2O |
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ICCT43 | Scientific Laboratory Supplies | 100ML | EUR 135.6 |
Strontium Pieces max. 8 mm, under oil, 99.2+% |
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GX0495-25 | Glentham Life Sciences | 25 | EUR 1023.2 |
IC Cation Std Strontium 1000ppm in 0.005% HNO3 |
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ICCB43 | Scientific Laboratory Supplies | 500ML | EUR 406.8 |
IC Cation Std Strontium 1000ppm in 0.005% HNO3 |
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ICCS43 | Scientific Laboratory Supplies | 100ML | EUR 157.98 |
IC Cation Std Strontium 100ppm in 0.005% HNO3 |
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ICCU43 | Scientific Laboratory Supplies | 100ML | EUR 137.09 |
Strontium acetate hydrate, 99+% |
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GX5175-100 | Glentham Life Sciences | 100 | EUR 126.5 |
Strontium chloride hydrate, 99.99+% |
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GX6973-10 | Glentham Life Sciences | 10 | EUR 172.7 |
Strontium nitrate, anhydrous, 98% |
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GK5693-1KG | Glentham Life Sciences | 1 kg | EUR 98.4 |
Strontium nitrate, anhydrous, 98% |
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GK5693-250G | Glentham Life Sciences | 250 g | EUR 60 |
Strontium nitrate, anhydrous, 98% |
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GK5693-5KG | Glentham Life Sciences | 5 kg | EUR 255.6 |
Strontium nitrate, anhydrous, 98% |
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GK5693-1 | Glentham Life Sciences | 1 | EUR 51.4 |
Strontium nitrate, anhydrous, 98% |
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GK5693-250 | Glentham Life Sciences | 250 | EUR 19.8 |
Strontium nitrate, anhydrous, 98% |
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GK5693-5 | Glentham Life Sciences | 5 | EUR 182 |
Strontium titanate Nanopowder, 99.9% |
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GX7135-1 | Glentham Life Sciences | 1 | EUR 633.8 |
Strontium titanate Nanopowder, 99.9% |
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GX7135-100 | Glentham Life Sciences | 100 | EUR 192.2 |
Strontium titanate Nanopowder, 99.9% |
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GX7135-250 | Glentham Life Sciences | 250 | EUR 281.9 |
Strontium titanate Nanopowder, 99.9% |
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GX7135-50 | Glentham Life Sciences | 50 | EUR 116.1 |
Strontium titanate-Nano Powder, 99.8% |
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GX8434-100 | Glentham Life Sciences | 100 | EUR 192.2 |
Strontium titanate-Nano Powder, 99.8% |
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GX8434-250 | Glentham Life Sciences | 250 | EUR 373 |
Strontium titanate-Nano Powder, 99.8% |
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GX8434-50 | Glentham Life Sciences | 50 | EUR 116.1 |
Strontium chloride hexahydrate |
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GK3876-1KG | Glentham Life Sciences | 1 kg | EUR 132 |
Strontium chloride hexahydrate |
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GK3876-500G | Glentham Life Sciences | 500 g | EUR 91.2 |
Strontium chloride hexahydrate |
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GK3876-5KG | Glentham Life Sciences | 5 kg | EUR 370.8 |
Strontium chloride hexahydrate |
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GK3876-1 | Glentham Life Sciences | 1 | EUR 79.1 |
Strontium chloride hexahydrate |
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GK3876-5 | Glentham Life Sciences | 5 | EUR 276.9 |
Strontium chloride hexahydrate |
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GK3876-500 | Glentham Life Sciences | 500 | EUR 45.9 |
Genistein |
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20-abx184098 | Abbexa |
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Genistein |
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1533-10 | Biovision | each | EUR 164.4 |
Genistein |
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1533-100 | Biovision | each | EUR 326.4 |
Genistein, >99% |
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BC033-101 | GenDepot | 1g | EUR 278.4 |
Genistein, >99% |
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BC033-105 | GenDepot | 5g | EUR 457.2 |
Genistein, >99% |
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BC033-110 | GenDepot | 10g | EUR 813.6 |
Genistein |
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A2198-100 | ApexBio | 100 mg | EUR 129.6 |
Description: Phytoestrogen with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase. Also binds to PPAR? and estrogen receptors and acts as an agonist at GPR30. Also available as part of the MAP |
Genistein |
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A2198-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Phytoestrogen with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase. Also binds to PPAR? and estrogen receptors and acts as an agonist at GPR30. Also available as part of the MAP |
Genistein |
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20-abx076504 | Abbexa |
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Genistein |
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GP7710-100MG | Glentham Life Sciences | 100 mg | EUR 180 |
Genistein |
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GP7710-10MG | Glentham Life Sciences | 10 mg | EUR 92.4 |
Genistein |
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GP7710-250MG | Glentham Life Sciences | 250 mg | EUR 237.6 |
Genistein |
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GP7710-50MG | Glentham Life Sciences | 50 mg | EUR 154.8 |
Genistein |
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GP7710-5MG | Glentham Life Sciences | 5 mg | EUR 74.4 |
Genistein |
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HY-14596 | MedChemExpress | 100mg | EUR 142.8 |
Genistein |
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40700024-1 | Bio-WORLD | 10 mg | EUR 29.83 |
Genistein |
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40700024-2 | Bio-WORLD | 25 mg | EUR 50.93 |
Genistein |
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40700024-3 | Bio-WORLD | 100 mg | EUR 117.63 |
Genistein |
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GP7710-10 | Glentham Life Sciences | 10 | EUR 74.7 |
Genistein |
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GP7710-100 | Glentham Life Sciences | 100 | EUR 118.7 |
Genistein |
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GP7710-250 | Glentham Life Sciences | 250 | EUR 180.9 |
Genistein |
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GP7710-5 | Glentham Life Sciences | 5 | EUR 31.7 |
Genistein |
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GP7710-50 | Glentham Life Sciences | 50 | EUR 116.1 |
Genistein |
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TB0320-0500 | ChemNorm | 8XX25mg | EUR 328.8 |
Genistein [CAS# 446-72-0] |
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G-6055 | LC LABORATORIES | 1 g | EUR 59 |
Strontium ranelate heptahydrate |
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20-abx184380 | Abbexa |
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Strontium hydroxide, octahydrate, 99+% |
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GX1288-1 | Glentham Life Sciences | 1 | EUR 101 |
Strontium hydroxide, octahydrate, 99+% |
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GX1288-500 | Glentham Life Sciences | 500 | EUR 84.4 |
Genistein 10mM |
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TG4160 | TopoGen | 0.25ml | EUR 187.2 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 500mL in 2% HCl |
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PLSR1-2X | Scientific Laboratory Supplies | 500ML | EUR 158.4 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 30mL in 2% HNO3 |
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PLSR2-2M | Scientific Laboratory Supplies | 30ML | EUR 34.8 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 250mL in 2% HNO3 |
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PLSR2-2T | Scientific Laboratory Supplies | 250ML | EUR 111.6 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 500mL in 2% HNO3 |
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PLSR2-2X | Scientific Laboratory Supplies | 500ML | EUR 144 |
Assurance Grade Strontium for AA and ICP 1000 ug/mL (1000 PPM) 125mL in 2% HNO3 |
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PLSR2-2Y01 | Scientific Laboratory Supplies | 125ML | EUR 64.8 |
Assurance Grade Strontium for AA and ICP 10000 ug/mL (10000 PPM) 500mL in 5% HNO3 |
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PLSR2-3X | Scientific Laboratory Supplies | 500ML | EUR 255.6 |
Assurance Grade Strontium for AA and ICP 10000 ug/mL (10000 PPM) 125mL in 5% HNO3 |
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PLSR2-3Y | Scientific Laboratory Supplies | 125ML | EUR 108 |
Strontium Chloride Diluting Solution |
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SRCL201 | Scientific Laboratory Supplies | 1L | EUR 72 |
Claritas PPT Grade Strontium for ICP-MS 1 ug/mL (1 PPM) 125mL in 2% HNO3 |
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CLSR2-1BY | Scientific Laboratory Supplies | 125ML | EUR 103.2 |
Kinesis Hollow Cathode Lamp Strontium 37mm Std |
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CHR6011 | Scientific Laboratory Supplies | EACH | EUR 334.23 |
Strontium chloride hexahydrate, 99%, ACS grade |
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GX3549-500G | Glentham Life Sciences | 500 g | EUR 122.4 |
Strontium chloride hexahydrate, 99%, ACS grade |
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GX3549-500 | Glentham Life Sciences | 500 | EUR 71.1 |
Strontium Pieces max. 20 mm, under argon, coated with oil, Ba max. 1%, 99% |
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GX0588-100 | Glentham Life Sciences | 100 | EUR 550.7 |
Genistein Solution |
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40140050-1 | Bio-WORLD | 1 mL | EUR 43.46 |
Kinesis Hollow Cathode Lamp Strontium 37mm unicam |
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CHR6015 | Scientific Laboratory Supplies | EACH | EUR 385.15 |
Kinesis Hollow Cathode Lamp Strontium 37mm Varian |
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CHR6017 | Scientific Laboratory Supplies | EACH | EUR 385.15 |
Familial dilated cardiomyopathy brought on by a novel variant within the Lamin A/C gene: a case report
Background: Familial dilated cardiomyopathy (FDCM) is mostly inherited as an autosomal dominant trait. The Lamin A/C (LMNA) gene variants have been recognized to be related to DCM, conductive system problems, kind 2 Emery-Dreifuss muscular dystrophy and a number of other different problems. Right here, we reported a novel variant within the LMNA gene that is likely to be associated to FDCM.
Case presentation: A 30-year-old younger man was hospitalized for chest tightness, excessive fatigue, palpitation and impaired exercise tolerance. He had scientific traits together with cardiac dilatation, atrial tachyarrhythmia, extreme conductive system problems, and dyskinesia of each higher limbs and the neck. Genetic sequence evaluation indicated that the affected person carried a novel c.1325 T>C heterozygous LMNA gene variant. Catheter ablation and cardiac resynchronization remedy with pacing perform (CRT-P) have been carried out to deal with the arrhythmia.
Conclusion: The variant c.1325 T>C is a novel variant within the LMNA gene that has not been beforehand reported. Younger sufferers with DCM, conductive system problems and skeletal myopathy ought to be alert to the potential for LMNA gene variant. Cardiac resynchronization remedy (CRT) could also be an affordable selection for affected person carrying a LMNA gene variant with third-degree atrioventricular block even when the left ventricular ejection fraction is preserved with the intention to stop the deterioration of cardiac perform brought on by proper ventricular pacing dependency.
Genetic evaluation of kids with congenital ocular anomalies in three ecological areas of Nepal: a section II of Nepal pediatric ocular illnesses research
Background: Genetic eye illnesses represent a big and heterogeneous group of childhood ocular morbidity. Particular person illnesses could trigger a number of structural anomalies and developmental options. Nepal Pediatric Ocular Illness Research (NPODS) was a population-based epidemiological research carried out throughout three ecological areas of Nepal to find out the prevalence and etiology of childhood ocular morbidity and blindness. In Part II of this research, genetic evaluation was carried out for kids who have been discovered to have congenital ocular anomalies.
Methodology: It was a cross sectional descriptive research. A complete of 10,270 youngsters throughout three totally different ecological areas in Nepal (Low lands, hills, and mountains) underwent ocular examinations in NPODS. Out of 374 (3.6%) of kids with ocular abnormalities, 30 have been considered congenital in nature. Focused genetic evaluation, together with genotyping for genes particular to presenting phenotype, was carried out for 25 youngsters utilizing serum samples.
Outcomes: Out of 25 youngsters, 18 had significant genetic outcomes. Evaluation revealed one missense alteration G12411T of Zinc Finger Homeobox 4 (ZFHX4) gene in a single participant amongst 10 with congenital ptosis and one other missense variation T > C P. Y374 C of Signaling Receptor and Transporter Retinol 6 (STRA6) gene in a single participant amongst Three with microphthalmos.
Conclusion: The research is first of its sort from Nepal and mutant genes have been distinctive to Nepalese Inhabitants. Additional evaluation of genetic components is essential to higher perceive genetic affiliation with ocular illnesses and situations. This helps additional in genetic counseling and doubtless gene remedy to forestall blindness from these situations.
Doxorubicin hydrochloride |
|||
ADC-P-014 | Creative Biolabs | unit | Ask for price |
Doxorubicin hydrochloride |
|||
GA4969-100MG | Glentham Life Sciences | 100 mg | EUR 217.2 |
Doxorubicin hydrochloride |
|||
GA4969-10MG | Glentham Life Sciences | 10 mg | EUR 93.6 |
Doxorubicin hydrochloride |
|||
GA4969-25MG | Glentham Life Sciences | 25 mg | EUR 117.6 |
Doxorubicin hydrochloride |
|||
GA4969-50MG | Glentham Life Sciences | 50 mg | EUR 151.2 |
Doxorubicin (hydrochloride) |
|||
HY-15142 | MedChemExpress | 100mg | EUR 176.4 |
Doxorubicin Hydrochloride |
|||
40410004-1 | Bio-WORLD | 10 mg | EUR 136.34 |
Doxorubicin Hydrochloride |
|||
40410004-2 | Bio-WORLD | 25 mg | EUR 273.17 |
Doxorubicin hydrochloride |
|||
TNC00267 | ChemNorm | 20mg | Ask for price |
Doxorubicin hydrochloride, 98% |
|||
GP9056-100 | Glentham Life Sciences | 100 | EUR 140.2 |
Doxorubicin hydrochloride, 98% |
|||
GP9056-25 | Glentham Life Sciences | 25 | EUR 56.1 |
Doxorubicin hydrochloride USP |
|||
D005-10MG | TOKU-E | 10 mg | EUR 199.2 |
Doxorubicin hydrochloride USP |
|||
D005-25MG | TOKU-E | 25 mg | EUR 361.2 |
Doxorubicin hydrochloride, USP grade |
|||
GA4969-10 | Glentham Life Sciences | 10 | EUR 47.4 |
Doxorubicin hydrochloride, USP grade |
|||
GA4969-100 | Glentham Life Sciences | 100 | EUR 150.4 |
Doxorubicin hydrochloride, USP grade |
|||
GA4969-25 | Glentham Life Sciences | 25 | EUR 67.2 |
Doxorubicin hydrochloride, USP grade |
|||
GA4969-50 | Glentham Life Sciences | 50 | EUR 95 |
Doxorubicin Hydrochloride (Autophagy inducer) |
|||
SIH-390-10MG | Stressmarq | 10 mg | EUR 231.6 |
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM).. |
Doxorubicin Hydrochloride (Autophagy inducer) |
|||
SIH-390-50MG | Stressmarq | 50 mg | EUR 634.8 |
Description: The substance Doxorubicin Hydrochloride is a autophagy inducer. It is synthetically produced and has a purity of >98%. The pure substance is red solid which is soluble in water (50 mM).. |
Doxorubicin |
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abx188695-1g | Abbexa | 1 g | EUR 560.4 |
Doxorubicin |
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A3966-10 | ApexBio | 10 mg | EUR 129.6 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
|||
A3966-100 | ApexBio | 100 mg | EUR 282 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
|||
A3966-25 | ApexBio | 25 mg | EUR 157.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
|||
A3966-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 157.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
|||
A3966-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin |
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ADC-P-013 | Creative Biolabs | unit | Ask for price |
Doxorubicin |
|||
D063-100MG | TOKU-E | 100 mg | EUR 1261.2 |
Doxorubicin |
|||
D063-25MG | TOKU-E | 25 mg | EUR 386.4 |
Doxorubicin |
|||
HY-15142A | MedChemExpress | 100mg | EUR 258 |
Doxorubicin |
|||
D063-5MG | TOKU-E | 5 mg | EUR 460.82 |
Description: C27H29NO11 |
Doxorubicin HCl |
|||
20-abx184016 | Abbexa |
|
|
Doxorubicin 10mM |
|||
TG4120 | TopoGen | 0.25ml | EUR 187.2 |
Doxorubicin HCl, 100mg |
|||
R2531-100mg | ACTGene | each | EUR 1560 |
Doxorubicin HCl, 10mg |
|||
R2531-10mg | ACTGene | each | EUR 236.4 |
Doxorubicin HCl, 100mg |
|||
R2531 | ACTGene | 100mg | EUR 1080.79 |
Adriamycin (Doxorubicin) |
|||
E1KS1208 | EnoGene | 10mg | EUR 490.8 |
Doxorubicin (Adriamycin) HCl |
|||
A1832-10 | ApexBio | 10 mg | EUR 150 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
|||
A1832-100 | ApexBio | 100 mg | EUR 560.4 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
|||
A1832-25 | ApexBio | 25 mg | EUR 226.8 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
Doxorubicin (Adriamycin) HCl |
|||
A1832-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. [1] It is an anthracycline antibiotic. It is been widely used in blood cancers, solid tumors and sarcomas. |
PEGylated Liposomal Doxorubicin- 2 mg |
|||
PHPC002DX | ProFoldin | 2 mg | EUR 140.62 |
Description: This product includes 1 ml of liposomal doxorubicin at concentrations of 2 mg/ml doxorubicin and 16 mg/ml of lipids. |
PEGylated Liposomal Doxorubicin- 20 mg |
|||
PHPC020DX | ProFoldin | 20 mg | EUR 358.62 |
Description: This product includes 10 ml of liposomal doxorubicin at concentrations of 2 mg/ml doxorubicin and 16 mg/ml of lipids. |
Human Doxorubicin-Stimulated HeLa Whole Cell Lysate |
|||
IHUHELADTLW500UG | Innovative research | each | EUR 327 |
Description: Human Doxorubicin-Stimulated HeLa Whole Cell Lysate |
Erlotinib, Hydrochloride Salt |
|||
1588-100 | Biovision | each | EUR 202.8 |
Erlotinib, Hydrochloride Salt |
|||
1588-1000 | Biovision | each | EUR 477.6 |
Human Doxorubicin-Stimulated HeLa Nuclear Extract Lysate |
|||
IHUHELADTLN200UG | Innovative research | each | EUR 427 |
Description: Human Doxorubicin-Stimulated HeLa Nuclear Extract Lysate |
Erlotinib, Hydrochloride Salt, >99% |
|||
BC026-101 | GenDepot | 1g | EUR 327.6 |
Erlotinib, Hydrochloride Salt, >99% |
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BC026-102 | GenDepot | 2g | EUR 465.6 |
Erlotinib, Hydrochloride Salt, >99% |
|||
BC026-105 | GenDepot | 5g | EUR 684 |
17-DMAG, Hydrochloride Salt, >98% |
|||
BC024-001 | GenDepot | 1mg | EUR 213.6 |
17-DMAG, Hydrochloride Salt, >98% |
|||
BC024-005 | GenDepot | 5mg | EUR 343.2 |
17-DMAG, Hydrochloride Salt, >98% |
|||
BC024-010 | GenDepot | 10mg | EUR 489.6 |
17-DMAG, Hydrochloride Salt, >98% |
|||
BC024-025 | GenDepot | 25mg | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
|||
BC024-100 | GenDepot | 100mg | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
|||
BC024-101 | GenDepot | 1g | Ask for price |
17-DMAG, Hydrochloride Salt, >99% |
|||
BC024-250 | GenDepot | 250mg | Ask for price |
OSU-03012, Hydrochloride Salt, >98% |
|||
BC061-005 | GenDepot | 5mg | EUR 375.6 |
OSU-03012, Hydrochloride Salt, >98% |
|||
BC061-025 | GenDepot | 25mg | EUR 634.8 |
Human HeLa (Cervix Adenocarcinoma) Whole Cell Lysate - Doxorubicin Stimulated |
|||
HCL-2010 | Alpha Diagnostics | 100ug | EUR 255.6 |
Alectinib, Hydrochloride Salt [CAS# 1256589-74-8] |
|||
A-2311 | LC LABORATORIES | 25 mg | EUR 49 |
Erlotinib, Hydrochloride Salt [CAS# 183319-69-9] |
|||
E-4007 | LC LABORATORIES | 500 mg | EUR 37 |
Pazopanib, Hydrochloride Salt [CAS# 635702-64-6] |
|||
P-6755 | LC LABORATORIES | 25 mg | EUR 46 |
Human HeLa (Cervix Adenocarcinoma) Cell Nuclear Extract - Doxorubicin Stimulated |
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HCL-2004 | Alpha Diagnostics | 100ug | EUR 270 |
Doxorubicin.HCl |
|||
1527-5 | Biovision | each | EUR 183.6 |
Epirubicin, Hydrochloride Salt [CAS# 56390-09-1] |
|||
E-8000 | LC LABORATORIES | 5 mg | EUR 37 |
Fingolimod, Hydrochloride Salt [CAS# 162359-56-0] |
|||
F-4633 | LC LABORATORIES | 100 mg | EUR 41 |
Gemcitabine, Hydrochloride Salt [CAS# 122111-03-9] |
|||
G-4177 | LC LABORATORIES | 100 mg | EUR 39 |
Palbociclib, Hydrochloride Salt [CAS# 827022-32-2] |
|||
P-7788 | LC LABORATORIES | 50 mg | EUR 39 |
Irinotecan, Hydrochloride Salt, Trihydrate [CAS# 136572-09-3] |
|||
I-4122 | LC LABORATORIES | 100 mg | EUR 39 |
L-Leucine 7-amido-4-methylcoumarin hydrochloride salt |
|||
GC8248-100 | Glentham Life Sciences | 100 | EUR 143.7 |
L-Leucine 7-amido-4-methylcoumarin hydrochloride salt |
|||
GC8248-25 | Glentham Life Sciences | 25 | EUR 57.8 |
Doxepin (hydrochloride) |
|||
C4153-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 135.6 |
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine. |
Doxepin (hydrochloride) |
|||
C4153-5000 | ApexBio | 5 g | EUR 201.6 |
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine. |
Doxepin (Hydrochloride) |
|||
HY-B0725 | MedChemExpress | 500mg | EUR 129.6 |
Doxapram hydrochloride |
|||
GP6685-100 | Glentham Life Sciences | 100 | EUR 201.9 |
Doxycycline Hydrochloride |
|||
D065-25MG | TOKU-E | 25mg | EUR 410.4 |
Doxycycline Hydrochloride |
|||
D065-5MG | TOKU-E | 5mg | EUR 142.8 |
Doxycycline hydrochloride |
|||
GA4252-1G | Glentham Life Sciences | 1 g | EUR 99.6 |
Doxycycline hydrochloride |
|||
GA4252-500MG | Glentham Life Sciences | 500 mg | EUR 74.4 |
Doxycycline (hydrochloride) |
|||
HY-N0565A | MedChemExpress | 1g | EUR 142.8 |
Doxycycline hydrochloride |
|||
GA4252-1 | Glentham Life Sciences | 1 | EUR 53.1 |
Doxycycline hydrochloride |
|||
GA4252-500 | Glentham Life Sciences | 500 | EUR 31.7 |
Doxycycline Hydrochloride |
|||
40410005-1 | Bio-WORLD | 10 g | EUR 92.3 |
Doxycycline Hydrochloride |
|||
40410005-2 | Bio-WORLD | 25 g | EUR 181.73 |
Doxapram (hydrochloride hydrate) |
|||
HY-B0551A | MedChemExpress | 10mM/1mL | EUR 206.4 |
(±)-Salsolinol (hydrochloride) |
|||
C4364-500 | ApexBio | 500 mg | EUR 369.6 |
Description: (±)-Salsolinol targets depolarize dopamineric neurons. Dopaminergic neurons produce dopamine, a neurotransmitter with various roles in neurological functions. |
2‐AMINO ACETAMIDE HYDROCHLORIDE (GLYCINAMIDE HYDROCHLORIDE) |
|||
101003 | Survival Technologies | each | Ask for price |
DOI hydrochloride |
|||
B5321-10 | ApexBio | 10 mg | EUR 205.2 |
DOI hydrochloride |
|||
B5321-5 | ApexBio | 5 mg | EUR 141.6 |
DOI hydrochloride |
|||
B5321-50 | ApexBio | 50 mg | EUR 714 |
DOB hydrochloride |
|||
B5344-1 | ApexBio | 1 mg | EUR 141.6 |
Q94 hydrochloride |
|||
B5705-10 | ApexBio | 10 mg | EUR 350.4 |
Q94 hydrochloride |
|||
B5705-50 | ApexBio | 50 mg | EUR 1264.8 |
GMQ hydrochloride |
|||
B5793-10 | ApexBio | 10 mg | EUR 212.4 |
GMQ hydrochloride |
|||
B5793-50 | ApexBio | 50 mg | EUR 711.6 |
AMT hydrochloride |
|||
B6480-10 | ApexBio | 10 mg | EUR 205.2 |
AMT hydrochloride |
|||
B6480-100 | ApexBio | 100 mg | EUR 1036.8 |
AMT hydrochloride |
|||
B6480-5 | ApexBio | 5 mg | EUR 141.6 |
AMT hydrochloride |
|||
B6480-50 | ApexBio | 50 mg | EUR 673.2 |
BEC (hydrochloride) |
|||
HY-19548A | MedChemExpress | 25mg | EUR 570 |
EDC hydrochloride |
|||
GP0849-100G | Glentham Life Sciences | 100 g | EUR 141.6 |
EDC hydrochloride |
|||
GP0849-250G | Glentham Life Sciences | 250 g | EUR 237.6 |
EDC hydrochloride |
|||
GP0849-25G | Glentham Life Sciences | 25 g | EUR 84 |
EDC hydrochloride |
|||
GP0849-5G | Glentham Life Sciences | 5 g | EUR 55.2 |
SAG (hydrochloride) |
|||
HY-12848B | MedChemExpress | 10mg | EUR 321.6 |
EDC hydrochloride |
|||
GP0849-100 | Glentham Life Sciences | 100 | EUR 87.1 |
EDC hydrochloride |
|||
GP0849-25 | Glentham Life Sciences | 25 | EUR 39.4 |
EDC hydrochloride |
|||
GP0849-250 | Glentham Life Sciences | 250 | EUR 166 |
EDC hydrochloride |
|||
GP0849-5 | Glentham Life Sciences | 5 | EUR 15.9 |
EDC Hydrochloride |
|||
40500004-1 | Bio-WORLD | 5 g | EUR 84.12 |
EDC Hydrochloride |
|||
40500004-2 | Bio-WORLD | 10 g | EUR 116.56 |
AMTB hydrochloride |
|||
B2978-25 | Biovision | 25 mg | EUR 812.4 |
AMTB hydrochloride |
|||
B2978-5 | Biovision | 5 mg | EUR 247.2 |
MPEP hydrochloride |
|||
B1151-10 | Biovision | each | EUR 222 |
MPEP hydrochloride |
|||
B1151-50 | Biovision | each | EUR 705.6 |
S1RA hydrochloride |
|||
B1180-10 | ApexBio | 10 mg | EUR 1144.8 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
|||
B1180-100 | ApexBio | 100 mg | EUR 4620 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
|||
B1180-5 | ApexBio | 5 mg | EUR 819.6 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
|||
B1180-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 895.2 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
|||
B1180-50 | ApexBio | 50 mg | EUR 3316.8 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
THZ1 Hydrochloride |
|||
B4736-10 | ApexBio | 10 mg | EUR 268.8 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
|||
B4736-25 | ApexBio | 25 mg | EUR 477.6 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
|||
B4736-5 | ApexBio | 5 mg | EUR 170.4 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
|||
B4736-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 205.2 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
EHNA hydrochloride |
|||
2265-25 | Biovision | each | EUR 339.6 |
EHNA hydrochloride |
|||
2265-5 | Biovision | each | EUR 138 |
TAME Hydrochloride |
|||
2050-100 | Biovision | each | EUR 151.2 |
TAME Hydrochloride |
|||
2050-1000 | Biovision | each | EUR 574.8 |
TAME Hydrochloride |
|||
2050-500 | Biovision | each | EUR 405.6 |
DMCM hydrochloride |
|||
B7268-10 | ApexBio | 10 mg | EUR 385.2 |
DMCM hydrochloride |
|||
B7268-100 | ApexBio | 100 mg | EUR 2210.4 |
DMCM hydrochloride |
|||
B7268-25 | ApexBio | 25 mg | EUR 776.4 |
DMCM hydrochloride |
|||
B7268-5 | ApexBio | 5 mg | EUR 277.2 |
DMCM hydrochloride |
|||
B7268-5.1 | ApexBio | 10 mM (in 1mL H2O) | EUR 297.6 |
DMCM hydrochloride |
|||
B7268-50 | ApexBio | 50 mg | EUR 1363.2 |
TRIS hydrochloride |
|||
B7299-500000 | ApexBio | 500 g | EUR 309.6 |
AMTB hydrochloride |
|||
B7559-10 | ApexBio | 10 mg | EUR 459.6 |
AMTB hydrochloride |
|||
B7559-50 | ApexBio | 50 mg | EUR 1746 |
MPEP Hydrochloride |
|||
A3633-10 | ApexBio | 10 mg | EUR 142.8 |
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system. |
MPEP Hydrochloride |
|||
A3633-50 | ApexBio | 50 mg | EUR 379.2 |
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system. |
MPTP hydrochloride |
|||
A3634-10 | ApexBio | 10 mg | EUR 162 |
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1]. |
MPTP hydrochloride |
|||
A3634-50 | ApexBio | 50 mg | EUR 344.4 |
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1]. |
MTEP hydrochloride |
|||
A3636-10 | ApexBio | 10 mg | EUR 205.2 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
MTEP hydrochloride |
|||
A3636-5 | ApexBio | 5 mg | EUR 153.6 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
MTEP hydrochloride |
|||
A3636-50 | ApexBio | 50 mg | EUR 686.4 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
PJ34 hydrochloride |
|||
A4159-10 | ApexBio | 10 mg | EUR 142.8 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
|||
A4159-5 | ApexBio | 5 mg | EUR 129.6 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
|||
A4159-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 150 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
|||
A4159-50 | ApexBio | 50 mg | EUR 296.4 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
|||
A4159-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
TCEP hydrochloride |
|||
B6055-10000 | ApexBio | 10 g | EUR 338.4 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
TCEP hydrochloride |
|||
B6055-2000 | ApexBio | 2 g | EUR 150 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
TCEP hydrochloride |
|||
B6055-50000 | ApexBio | 50 g | EUR 1243.2 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
HEAT hydrochloride |
|||
B6339-10 | ApexBio | 10 mg | EUR 321.6 |
HEAT hydrochloride |
|||
B6339-50 | ApexBio | 50 mg | EUR 1167.6 |
THIP hydrochloride |
|||
B6460-100 | ApexBio | 100 mg | EUR 358.8 |
THIP hydrochloride |
|||
B6460-25 | ApexBio | 25 mg | EUR 174 |
THIP hydrochloride |
|||
B6460-50 | ApexBio | 50 mg | EUR 243.6 |
EHNA hydrochloride |
|||
B6662-10 | ApexBio | 10 mg | EUR 145.2 |
EHNA hydrochloride |
|||
B6662-25 | ApexBio | 25 mg | EUR 262.8 |
N20C hydrochloride |
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B6980-10 | ApexBio | 10 mg | EUR 340.8 |
N20C hydrochloride |
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B6980-50 | ApexBio | 50 mg | EUR 1245.6 |
TMPH hydrochloride |
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B7053-10 | ApexBio | 10 mg | EUR 321.6 |
TMPH hydrochloride |
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B7053-50 | ApexBio | 50 mg | EUR 1167.6 |
DAPI (hydrochloride) |
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C3362-10 | ApexBio | 10 mg | EUR 146.4 |
DAPI (hydrochloride) |
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C3362-25 | ApexBio | 25 mg | EUR 240 |
DAPI (hydrochloride) |
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C3362-5 | ApexBio | 5 mg | EUR 111.6 |
AD57 (hydrochloride) |
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C3080-1 | ApexBio | 1 mg | EUR 141.6 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
AD57 (hydrochloride) |
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C3080-10 | ApexBio | 10 mg | EUR 714 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
AD57 (hydrochloride) |
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C3080-5 | ApexBio | 5 mg | EUR 428.4 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
MMAD hydrochloride |
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ADC-P-019 | Creative Biolabs | unit | Ask for price |
MMAF Hydrochloride |
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ADC-P-021 | Creative Biolabs | unit | Ask for price |
THZ1 hydrochloride |
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9544-25 | Biovision | each | EUR 1227.6 |
THZ1 hydrochloride |
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9544-5 | Biovision | each | EUR 366 |
TRIS hydrochloride |
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GB4431-100G | Glentham Life Sciences | 100 g | EUR 64.8 |