iowaodes

Single cell transcriptomes reveal expression patterns of chemoreceptor genes in olfactory sensory neurons of the Caribbean

An embedded gene selection method using knockoffs optimizing neural network

 

Background: Gene choice refers to discover a small subset of discriminant genes from the gene expression profiles. The way to choose genes that have an effect on particular phenotypic traits successfully is a vital analysis work within the subject of biology. The neural community has higher becoming capability when coping with nonlinear information, and it will probably seize options robotically and flexibly. On this work, we suggest an embedded gene choice methodology utilizing neural community.

 

The essential genes may be obtained by calculating the burden coefficient after the coaching is accomplished. In an effort to remedy the issue of black field of neural community and additional make the coaching outcomes interpretable in neural community, we use the concept of knockoffs to assemble the knockoff characteristic genes of the unique characteristic genes. This methodology not solely make every characteristic gene to compete with one another, but additionally make every characteristic gene compete with its knockoff characteristic gene. This method may help to pick the important thing genes that have an effect on the decision-making of neural networks.

 

Outcomes: We use maize carotenoids, tocopherol methyltransferase, raffinose household oligosaccharides and human breast most cancers dataset to do verification and evaluation.

 

Conclusions: The experiment outcomes display that the knockoffs optimizing neural community methodology has higher detection impact than the opposite present algorithms, and specifically for processing the nonlinear gene expression and phenotype information.

 

iowaodes
iowaodes

Fenretinide

A3412-10 10 mg
EUR 38
Description: Synthetic retinoid agonist

Fenretinide

A3412-5.1 10 mM (in 1mL DMSO)
EUR 40
Description: Synthetic retinoid agonist

Fenretinide

A3412-50 50 mg
EUR 59
Description: Synthetic retinoid agonist

Fenretinide

9417-10 each
EUR 222

Fenretinide

9417-50 each
EUR 705.6

Fenretinide

T1872-10mg 10mg Ask for price
Description: Fenretinide

Fenretinide

T1872-1g 1g Ask for price
Description: Fenretinide

Fenretinide

T1872-1mg 1mg Ask for price
Description: Fenretinide

Fenretinide

T1872-50mg 50mg Ask for price
Description: Fenretinide

Fenretinide

T1872-5mg 5mg Ask for price
Description: Fenretinide

Fenretinide

HY-15373 10mM/1mL
EUR 151.2

Fenretinide-d4

F250002 25mg
EUR 1200

Fenretinide (4-HPR)

abx282632-100g 100 µg Ask for price

Fenretinide (4-HPR)

abx282632-20g 20 µg
EUR 143.75

Fenretinide (4-HPR)

abx282632-50g 50 µg
EUR 362.5

3-Hydroxy Fenretinide

H825635 50mg
EUR 4500
Description: 1027233-22-2

Fenretinide [CAS# 65646-68-6]

F-4077 10 mg
EUR 39

4-Methoxy Fenretinide-13C,d3

M262662 25mg
EUR 3000

3-Hydroxy Fenretinide-d4

H825637 25mg
EUR 4500

4-Methoxy Fenretinide-d4

M262661 10mg
EUR 1200

Fenretinide Glucuronide Monosodium Salt

F250010 500mg
EUR 11200
Description: 76177-99-6

Fenretinide Glucuronide Monosodium Salt-d4

F250012 100mg
EUR 11200

13-cis-Fenretinide

F250005 100mg
EUR 1455
Description: 75686-07-6

13-cis-Fenretinide-d4

F250007 25mg
EUR 1200

Fen1/ Rat Fen1 ELISA Kit

ELI-27513r 96 Tests
EUR 1063.2

1000 ug/mL Fenthion in Acetone - 1ML

S-2010-AC 1ML
EUR 189

1000 ug/mL Fenobucarb in Acetone - 1ML

S-4610-AC 1ML
EUR 106.65

FEN1

enz-468 5µg
EUR 60
Description: Recombinant Human Flap Structure-Specific Endonuclease 1

FEN1

CSB-CL008585HU 10 μg plasmid + 200μl Glycerol Ask for price

1000 ug/mL Fenpyroximate in Acetone - 1ML

S-5804 1ML
EUR 259.2

FEN1 siRNA

20-abx916746
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

FEN1 siRNA

20-abx916747
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

FEN1-IN-2

T40931-10mg 10mg Ask for price
Description: FEN1-IN-2

FEN1-IN-2

T40931-1g 1g Ask for price
Description: FEN1-IN-2

FEN1-IN-2

T40931-1mg 1mg Ask for price
Description: FEN1-IN-2

FEN1-IN-2

T40931-50mg 50mg Ask for price
Description: FEN1-IN-2

FEN1-IN-2

T40931-5mg 5mg Ask for price
Description: FEN1-IN-2

FEN1-IN-3

T9147-10mg 10mg Ask for price
Description: FEN1-IN-3

FEN1-IN-3

T9147-1g 1g Ask for price
Description: FEN1-IN-3

FEN1-IN-3

T9147-1mg 1mg Ask for price
Description: FEN1-IN-3

FEN1-IN-3

T9147-50mg 50mg Ask for price
Description: FEN1-IN-3

FEN1-IN-3

T9147-5mg 5mg Ask for price
Description: FEN1-IN-3

FEN1-IN-4

T8545-1mg 1mg Ask for price
Description: FEN1-IN-4

FEN1-IN-4

T8545-50mg 50mg Ask for price
Description: FEN1-IN-4

FEN1-IN-4

T8545-5mg 5mg Ask for price
Description: FEN1-IN-4

FEN1-IN-4

T8545-10mg 10mg Ask for price
Description: FEN1-IN-4

FEN1-IN-4

T8545-1g 1g Ask for price
Description: FEN1-IN-4

FEN1-IN-1

T15274-10mg 10mg Ask for price
Description: FEN1-IN-1

FEN1-IN-1

T15274-1g 1g Ask for price
Description: FEN1-IN-1

FEN1-IN-1

T15274-1mg 1mg Ask for price
Description: FEN1-IN-1

FEN1-IN-1

T15274-50mg 50mg Ask for price
Description: FEN1-IN-1

FEN1-IN-1

T15274-5mg 5mg Ask for price
Description: FEN1-IN-1

Lenti ORF particles, Fen1 (GFP-tagged ORF) - Rat flap structure-specific endonuclease 1 (Fen1), 200ul, >10^7 TU/mL

RR207787L4V 200 µl Ask for price

Lenti ORF particles, Fen1 (GFP-tagged) - Mouse flap structure specific endonuclease 1 (Fen1), 200ul, >10^7 TU/mL

MR220960L4V 200 µl Ask for price

1000 ug/mL Fenamidone in HPLC Acetonitrile - 1ML

LCS-4966 1ML
EUR 390.15

1000 ug/mL Fenazaquin in HPLC Acetonitrile - 1ML

LCS-6019 1ML
EUR 398.25

1000 ug/mL of Fenitrothion in Acetone 1mL Ampule - 1ML

S-2001 1ML
EUR 67.5

Lenti ORF particles, FEN1 (Myc-DDK tagged) - Human flap structure-specific endonuclease 1 (FEN1), 200ul, >10^7 TU/mL

RC201785L1V 200 µl Ask for price

Lenti ORF particles, FEN1 (mGFP-tagged) - Human flap structure-specific endonuclease 1 (FEN1), 200ul, >10^7 TU/mL

RC201785L2V 200 µl Ask for price

Lenti ORF particles, FEN1 (Myc-DDK tagged) - Human flap structure-specific endonuclease 1 (FEN1), 200ul, >10^7 TU/mL

RC201785L3V 200 µl Ask for price

Lenti ORF particles, FEN1 (mGFP-tagged) - Human flap structure-specific endonuclease 1 (FEN1), 200ul, >10^7 TU/mL

RC201785L4V 200 µl Ask for price

Lenti ORF particles, Fen1 (Myc-DDK-tagged) - Mouse flap structure specific endonuclease 1 (Fen1), 200ul, >10^7 TU/mL

MR220960L3V 200 µl Ask for price

FEN1 protein

30R-1442 100 ug
EUR 410
Description: Purified recombinant Human FEN1 protein

FEN1 Rabbit pAb

E2381904 100ul
EUR 225
Description: Available in various conjugation types.

FEN1 Rabbit pAb

E2501175 100ul
EUR 225
Description: Available in various conjugation types.

FEN1 Rabbit mAb

E2R26747 100ul
EUR 255
Description: Available in various conjugation types.

FEN1 Rabbit pAb

A0129-100ul 100 ul
EUR 369.6

FEN1 Rabbit pAb

A0129-200ul 200 ul
EUR 550.8

FEN1 Rabbit pAb

A0129-20ul 20 ul Ask for price

FEN1 Rabbit pAb

A0129-50ul 50 ul Ask for price

FEN1 Rabbit pAb

A1175-100ul 100 ul
EUR 369.6

FEN1 Rabbit pAb

A1175-200ul 200 ul
EUR 550.8

FEN1 Rabbit pAb

A1175-20ul 20 ul
EUR 219.6

FEN1 Rabbit pAb

A1175-50ul 50 ul
EUR 267.6

FEN1 Rabbit mAb

59492 100ul
EUR 339

FEN1 Rabbit mAb

52758 100ul
EUR 499

FEN-1 Rabbit mAb

A8999 20 μL
EUR 128.7
Description: A synthetic peptide corresponding to a sequence within amino acids 5000-5100 of human MUC2 (Q02817).

FEN1 Rabbit mAb

E2R381904 100ul
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

1000 ug/mL (E)-Fenpyroximate in Acetonitrile - 1ML

S-6179 1ML
EUR 136.35

Fen1 (untagged ORF) - Rat flap structure-specific endonuclease 1 (Fen1), (10 ug)

RN207787 10 µg Ask for price

Lenti ORF particles, Fen1 (Myc-DDK-tagged ORF) - Rat flap structure-specific endonuclease 1 (Fen1), 200ul, >10^7 TU/mL

RR207787L3V 200 µl Ask for price

Fen1 (untagged) - Mouse flap structure specific endonuclease 1 (Fen1), (10ug)

MC208478 10 µg Ask for price

FEN1 (GFP-tagged) - Human flap structure-specific endonuclease 1 (FEN1)

RG201785 10 µg Ask for price

FEN1 (untagged)-Human flap structure-specific endonuclease 1 (FEN1)

SC110892 10 µg Ask for price

Fen1 (GFP-tagged) - Mouse flap structure specific endonuclease 1 (Fen1), (10ug)

MG220960 10 µg Ask for price

FEN1 antibody

10R-1738 100 ug
EUR 614.4
Description: Mouse monoclonal FEN1 antibody

FEN1 Antibody

32204 100ul
EUR 439

FEN1 Antibody

32204-100ul 100ul
EUR 302.4

FEN1 Antibody

33763 100ul
EUR 319

FEN1 Antibody

33763-100ul 100ul
EUR 302.4

FEN1 Antibody

33763-50ul 50ul
EUR 224.4

FEN1 Antibody

CSB-PA926648- each
EUR 402
Description: A polyclonal antibody against FEN1. Recognizes FEN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

FEN1 Antibody

CSB-PA926648-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against FEN1. Recognizes FEN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

FEN1 Antibody

E033763 100μg/100μl
EUR 255
Description: Available in various conjugation types.

FEN1 Antibody

E19-3172 100μg/100μl
EUR 225
Description: Available in various conjugation types.

FEN1 Antibody

E19-6309 100μg/100μl
EUR 225
Description: Available in various conjugation types.

FEN1 Antibody

E11-10585C 100μg
EUR 225
Description: Available in various conjugation types.

FEN1 Antibody

E38PA1417 100ul
EUR 225
Description: Available in various conjugation types.

FEN1 Antibody

E91175 100ul
EUR 255
Description: Available in various conjugation types.

FEN1 Antibody

GWB-5BB6C0 0.1 mg Ask for price

FEN1 Antibody

DF6309 200ul
EUR 420

FEN1 Antibody

DF6309-100ul 100ul
EUR 280

FEN1 Antibody

DF6309-200ul 200ul
EUR 350

FEN1 Antibody

DF3172 200ul
EUR 420

FEN1 Antibody

E309179 200ul
EUR 275
Description: Available in various conjugation types.

FEN1 Antibody

1-CSB-PA002510
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against FEN1. Recognizes FEN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

FEN1 Antibody

1-CSB-PA008585GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against FEN1. Recognizes FEN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

FEN1 Antibody

CSB-PA008585KA01HU- each
EUR 402
Description: A polyclonal antibody against FEN1. Recognizes FEN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

FEN1 Antibody

CSB-PA008585KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against FEN1. Recognizes FEN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

FEN1 antibody

70R-1605 100 ug
EUR 407
Description: Rabbit polyclonal FEN1 antibody raised against the C terminal of FEN1

FEN1 antibody

70R-17281 50 ul
EUR 289
Description: Rabbit polyclonal FEN1 antibody

FEN1 antibody

70R-49736 100 ul
EUR 242
Description: Purified Polyclonal FEN1 antibody

FEN1 antibody

70R-31706 100 ug
EUR 294
Description: Rabbit polyclonal FEN1 antibody

FEN1 Antibody

ABD13091 100 ug
EUR 525.6

FEN1 Antibody

ABD3172 100 ug
EUR 525.6

FEN1 Antibody

ABD6309 100 ug
EUR 525.6

FEN1 Antibody

CAC11682-100ul 100ul
EUR 314

FEN1 Antibody

CAC11682-50ul 50ul
EUR 199.2

FEN1 Antibody

8C10585 50ug
EUR 368
Description: FEN1 Antibody

FEN-1 Antibody

RQ5695 100 ug
EUR 356.15
Description: Flap endonuclease 1 is an enzyme that in humans is encoded by the FEN1 gene. It is mapped to 11q12.2. The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.

FEN1-IN-SC13

T9743-10mg 10mg Ask for price
Description: FEN1-IN-SC13

FEN1-IN-SC13

T9743-1g 1g Ask for price
Description: FEN1-IN-SC13

FEN1-IN-SC13

T9743-1mg 1mg Ask for price
Description: FEN1-IN-SC13

FEN1-IN-SC13

T9743-50mg 50mg Ask for price
Description: FEN1-IN-SC13

FEN1-IN-SC13

T9743-5mg 5mg Ask for price
Description: FEN1-IN-SC13

FEN1 Antibody

GWB-8C5945 0.1 mg Ask for price

FEN1 Antibody

GWB-670BF0 0.1 ml Ask for price

FEN1 Antibody

GWB-MQ320E 50ug Ask for price

FEN1 Antibody

GWB-MQ321F 100ug Ask for price

FEN1 Antibody

abx243080-96tests 96 tests
EUR 287.5

1000 ug/mL (E)-Fenpyroximate in HPLC Acetonitrile - 1ML

LCS-6179 1ML
EUR 398.25

1000 ug/mL Fenpyroximate in HPLC Acetonitrile - 1ML

LCS-6387 1ML
EUR 218.7

1000 ug/mL Fenthion sulfoxide in Acetonitrile - 1ML

S-4316-ACN 1ML
EUR 125.55

Fen1 (Myc-DDK-tagged ORF) - Rat flap structure-specific endonuclease 1 (Fen1), (10 ug)

RR207787 10 µg Ask for price

Fen1 (Myc-DDK-tagged) - Mouse flap structure specific endonuclease 1 (Fen1)

MR220960 10 µg Ask for price

FEN1 ELISA KIT|Human

EF009610 96 Tests
EUR 826.8

FEN1 (Myc-DDK-tagged)-Human flap structure-specific endonuclease 1 (FEN1)

RC201785 10 µg Ask for price

1000 ug/mL Fenthion-sulfone in HPLC Acetonitrile - 1ML

LCS-6063 1ML
EUR 330.75

anti- FEN1 antibody

FNab03075 100µg
EUR 606.3
Description: Antibody raised against FEN1

Fen1 ORF Vector (Rat) (pORF)

ORF067064 1.0 ug DNA
EUR 607.2

Lenti ORF clone of Fen1 (mGFP-tagged) - Mouse flap structure specific endonuclease 1 (Fen1)

MR220960L4 10 µg Ask for price

FEN1 (Center) Rabbit pAb

E2614818 100ul
EUR 225
Description: Available in various conjugation types.

Rat FEN1 shRNA Plasmid

20-abx986959
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

1000 ug/mL Fensulfothion-oxon in HPLC Acetonitrile - 1ML

LCS-6209 1ML
EUR 724.95

1000 ug/mL Fenhexamid in Acetonitrile Volume: 1mL Ampule - 1ML

S-4962-ACN 1ML
EUR 130.95

1000 ug/mL Fenamidone in Acetonitrile Volume: 1mL Ampule - 1ML

S-4966-ACN 1ML
EUR 136.35

Lenti ORF clone of Fen1 (mGFP-tagged ORF) - Rat flap structure-specific endonuclease 1 (Fen1), (10 ug)

RR207787L4 10 µg Ask for price

Lenti ORF clone of Fen1 (Myc-DDK-tagged) - Mouse flap structure specific endonuclease 1 (Fen1)

MR220960L3 10 µg Ask for price

FEN1 cloning plasmid

CSB-CL008585HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the FEN1 gene.

Fen1 ORF Vector (Mouse) (pORF)

ORF044773 1.0 ug DNA
EUR 607.2

FEN1 ORF Vector (Human) (pORF)

ORF004018 1.0 ug DNA
EUR 114

Fen1 3'UTR GFP Stable Cell Line

TU156502 1.0 ml Ask for price

FEN1 3'UTR GFP Stable Cell Line

TU057883 1.0 ml
EUR 1672.8

Fen1 3'UTR GFP Stable Cell Line

TU254569 1.0 ml Ask for price

Lenti ORF clone of Fen1 (Myc-DDK-tagged ORF) - Rat flap structure-specific endonuclease 1 (Fen1), (10 ug)

RR207787L3 10 µg Ask for price

Fen1 (untagged) - Mouse flap structure specific endonuclease 1 (Fen1), transcript variant 2

MC227399 10 µg Ask for price

Fen1 (untagged) - Mouse flap structure specific endonuclease 1 (Fen1), transcript variant 3

MC227400 10 µg Ask for price

FEN1 Blocking Peptide

33R-7232 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FEN1 antibody, catalog no. 70R-1605

FEN1 Blocking Peptide

DF6309-BP 1mg
EUR 234

FEN1 Blocking Peptide

DF3172-BP 1mg
EUR 234

Human FEN1 shRNA Plasmid

20-abx951559
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

FEN1 Blocking Peptide

20-abx062611
  • Ask for price
  • Ask for price
  • 1 mg
  • 5 mg

Rad2 / FEN1 (pS187) Antibody

abx215327-100ug 100 ug
EUR 526.8

FEN1P1 ORF Vector (Human) (pORF)

ORF019564 1.0 ug DNA Ask for price

Fen1 (myc-DDK-tagged) - Mouse flap structure specific endonuclease 1 (Fen1), transcript variant 2

MR229610 10 µg Ask for price

Fen1 (myc-DDK-tagged) - Mouse flap structure specific endonuclease 1 (Fen1), transcript variant 3

MR229611 10 µg Ask for price

1000 ug/mL Fenbutatin-oxide in LCMS Grade AcetoneVolume: 1mL Ampule - 1ML

LCS-1999-AC 1ML
EUR 244.35

1000 ug/mL Fensulfothion-oxon-sulfone in HPLC Acetonitrile - 1ML

LCS-6210 1ML
EUR 414.45

FEN-1 Polyclonal Antibody

40922-100ul 100ul
EUR 302.4

FEN-1 Polyclonal Antibody

40922-50ul 50ul
EUR 224.4

FEN-1 Polyclonal Antibody

E040922 100μg/100μl
EUR 255
Description: Available in various conjugation types.

FEN-1 Polyclonal Antibody

E20-71689 100ug
EUR 225
Description: Available in various conjugation types.

FEN1 Conjugated Antibody

C32204 100ul
EUR 476.4

FEN-1 Polyclonal Antibody

ABP51337-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of FEN-1 from Human, Mouse, Rat. This FEN-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FEN-1 at AA range: 60-140

FEN-1 Polyclonal Antibody

ABP51337-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of FEN-1 from Human, Mouse, Rat. This FEN-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FEN-1 at AA range: 60-140

FEN-1 Polyclonal Antibody

ABP51337-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of FEN-1 from Human, Mouse, Rat. This FEN-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FEN-1 at AA range: 60-140

Human FEN1 Protein Lysate 20ug

IHUFEN1PLLY20UG each
EUR 213
Description: Human FEN1 Protein Lysate 20ug

FEN1 ELISA Kit (Human) (OKEH08213)

OKEH08213 96 Wells
EUR 1075.2
Description: Description of target: The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Competitive ELISA;Sensitivity: 0.136ng/mL

Fen1 ELISA Kit (Mouse) (OKEH08214)

OKEH08214 96 Wells
EUR 1075.2
Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.27ng/mL

FEN1 Protein Vector (Rat) (pPM-C-HA)

PV268256 500 ng
EUR 723.6

FEN-1 Polyclonal Antibody

E44H04707 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

FEN1 Polyclonal Antibody

E-AB-60232-120uL 120uL
EUR 320
Description: Unconjugated

FEN1 Polyclonal Antibody

E-AB-60232-200uL 200uL
EUR 530
Description: Unconjugated

FEN1 Polyclonal Antibody

E-AB-60232-60uL 60uL
EUR 200
Description: Unconjugated

FEN1 Polyclonal Antibody

E-AB-60232-each each Ask for price
Description: Unconjugated

FEN1 Protein Vector (Rat) (pPB-C-His)

PV268254 500 ng
EUR 723.6

FEN1 Protein Vector (Rat) (pPB-N-His)

PV268255 500 ng
EUR 723.6

FEN1 Protein Vector (Rat) (pPM-C-His)

PV268257 500 ng
EUR 723.6

OPPA02024-5UG - FEN1 Protein

OPPA02024-5UG 5ug
EUR 70

FEN1 Recombinant Protein (Rat)

RP201188 100 ug Ask for price

FEN1 (A119) polyclonal antibody

E43S1989 100ul
EUR 225
Description: Available in various conjugation types.

AAP46097-100UG - FEN1 Peptide

AAP46097-100UG 100ug
EUR 99

FEN1 Protein Vector (Human) (pPM-C-HA)

PV016071 500 ng
EUR 394.8

FEN1 Protein Vector (Mouse) (pPM-C-HA)

PV179092 500 ng
EUR 723.6

Rad2/FEN1 (Phospho- Ser187) Antibody

ABF8505 100 ug
EUR 525.6

 

Single cell transcriptomes reveal expression patterns of chemoreceptor genes in olfactory sensory neurons of the Caribbean spiny lobster, Panulirus argus

 

 

Background: Crustaceans categorical a number of courses of receptor genes of their antennules, which home olfactory sensory neurons (OSNs) and non-olfactory chemosensory neurons. Transcriptomics research reveal that candidate chemoreceptor proteins embrace variant Ionotropic Receptors (IRs) together with each co-receptor IRs and tuning IRs, Transient Receptor Potential (TRP) channels, Gustatory Receptors, epithelial sodium channels, and sophistication A G-protein coupled receptors (GPCRs). The Caribbean spiny lobster, Panulirus argus, expresses in its antennules almost 600 IRs, 17 TRP channels, 1 Gustatory Receptor, 7 epithelial sodium channels, 81 GPCRs, 6 G proteins, and dozens of enzymes in signaling pathways.

 

Nevertheless, the precise combinatorial expression patterns of those proteins in single sensory neurons usually are not recognized for any crustacean, limiting our understanding of how their chemosensory techniques encode chemical high quality.

 

Outcomes: The purpose of this research was to make use of transcriptomics to explain expression patterns of chemoreceptor genes in OSNs of P. argus. We generated and analyzed transcriptomes from 7 single OSNs, a few of which have been proven to answer a meals odor, in addition to a further 7 multicell transcriptomes from preparations containing few (2-4), a number of (ca. 15), or many (ca. 400) OSNs. We discovered that every OSN expressed the identical 2 co-receptor IRs (IR25a, IR93a) however

 

not the opposite 2 antennular coIRs (IR8a, IR76b), 9-53 tuning IRs however just one to some in excessive abundance, the identical 5 TRP channels plus as much as 5 extra TRPs, 12-17 GPCRs together with the identical 5 expressed in each single cell transcriptome, the identical Three G proteins plus others, many enzymes within the signaling pathways, however no Gustatory Receptors or epithelial sodium channels. The best distinction in receptor expression among the many OSNs was the identification of the tuning IRs.

 

Conclusions: Our outcomes present an preliminary view of the combinatorial expression patterns of receptor molecules in single OSNs in a single species of decapod crustacean, together with receptors straight concerned in olfactory transduction and others doubtless concerned in modulation. Our outcomes additionally counsel variations in receptor expression in OSNs vs. different chemosensory neurons.

Camel Genetic Assets Conservation by Tourism: A Key Sociocultural Method of Camelback Leisure Driving

 

  • Camels are unique parts, which may be comprised inside journey journey corporations selling ecotourism actions. Such recreations contribute to sustainable livelihoods for native communities and academic empowerment in the direction of nature and its conservation. At current, some native camel breeds’ survival reduces to this animal-based leisure business and its reliability to carry out and promote custom-made companies By conducting an on-site questionnaire to prospects taking part in camelback driving excursions, we assessed the motivational components affecting participation, satisfaction, and loyalty on this tourism phase that will have made it socially differentiated.

 

  • The sixfold mixture of workers efficiency, tradition geography, numerous and humane shut interplay, camel conduct and efficiency, sociotemporal context, and constructive earlier expertise includes the fundamental dimensions that designate buyer satisfaction and return intention chance inside this leisure enterprise.

 

  • Buyer data is crucial for stakeholders to construct personalised driving experiences and align income with environmental sustainability and biodiversity mainstream considerations into their on a regular basis operations. In flip, home camel vacationer rides might be managed as a viable path to nature conservation by serving to endangered native breeds to keep away from their useful devaluation and potential extinction.

 

Afatinib

27009 25 mg
EUR 115
Description: Afatinib, also known as BIW-2992, is an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinases. Afatinib suppresses EGF-induced EGFR phosphorylation and cellular proliferation in various cell lines, including EGFR-overexpressing and HER2-expressing cell lines A431, NIH-3T3-HER2, NCI-N87 and BT-474.

Afatinib

A355300 100mg
EUR 68
Description: 850140-72-6

Afatinib

A170-100MG 100mg
EUR 62.04
Description: C24H25ClFN5O3

Afatinib

GW6150-1 1
EUR 171.5

Afatinib

GW6150-10 10
EUR 368.2

Afatinib

GW6150-5 5
EUR 237.4

Afatinib

HY-10261 200mg
EUR 374.4

Afatinib

T21312-10mg 10mg Ask for price
Description: Afatinib

Afatinib

T21312-1g 1g Ask for price
Description: Afatinib

Afatinib

T21312-1mg 1mg Ask for price
Description: Afatinib

Afatinib

T21312-50mg 50mg Ask for price
Description: Afatinib

Afatinib

T21312-5mg 5mg Ask for price
Description: Afatinib

(R)-Afatinib

C597485 10mg
EUR 969
Description: 945553-91-3

(2Z)-Afatinib

A355305 0.5mg
EUR 2113
Description: 1680184-59-1

Afatinib D6

T10256-10mg 10mg Ask for price
Description: Afatinib D6

Afatinib D6

T10256-1g 1g Ask for price
Description: Afatinib D6

Afatinib D6

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Description: Afatinib D6

Afatinib D6

T10256-50mg 50mg Ask for price
Description: Afatinib D6

Afatinib D6

T10256-5mg 5mg Ask for price
Description: Afatinib D6

Afatinib-d4

A355302 25mg
EUR 15000

Afatinib-d6

A355303 10mg
EUR 628
Description: 1313874-96-2

Afatinib Dimer

A355310 25mg
EUR 12800

Afatinib oxalate

T64075-10mg 10mg Ask for price
Description: Afatinib oxalate

Afatinib oxalate

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Description: Afatinib oxalate

Afatinib oxalate

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Description: Afatinib oxalate

Afatinib oxalate

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Description: Afatinib oxalate

Afatinib oxalate

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Description: Afatinib oxalate

Afatinib (BIBW2992)

A8247-10 10 mg
EUR 62
Description: Irreversible EGFR/HER2 inhibitor

Afatinib (BIBW2992)

A8247-5 5 mg
EUR 37
Description: Irreversible EGFR/HER2 inhibitor

Afatinib (BIBW2992)

A8247-5.1 10 mM (in 1mL DMSO)
EUR 55
Description: Irreversible EGFR/HER2 inhibitor

Afatinib (BIBW2992)

A8247-50 50 mg
EUR 86
Description: Irreversible EGFR/HER2 inhibitor

Afatinib (BIBW2992)

A8247-S Evaluation Sample
EUR 22
Description: Irreversible EGFR/HER2 inhibitor

BIBW 2992 (Afatinib)

abx283009-100g 100 µg Ask for price

BIBW 2992 (Afatinib)

abx283009-20g 20 µg
EUR 156.25

BIBW 2992 (Afatinib)

abx283009-50g 50 µg
EUR 387.5

Afatinib dimaleate

120204 100.0mg
EUR 90

Afatinib Dimaleate

A355315 1g
EUR 126
Description: 850140-73-7

Afatinib dimaleate

A3145-10 10 mg
EUR 54
Description: EGFR inhibitor

Afatinib dimaleate

A3145-5 5 mg
EUR 33
Description: EGFR inhibitor

Afatinib dimaleate

A3145-5.1 10 mM (in 1mL DMSO)
EUR 48
Description: EGFR inhibitor

Afatinib dimaleate

A3145-50 50 mg
EUR 78
Description: EGFR inhibitor

Afatinib (dimaleate)

HY-10261A 200mg
EUR 374.4

Afatinib Dimaleate

T1773-10mg 10mg Ask for price
Description: Afatinib Dimaleate

Afatinib Dimaleate

T1773-1g 1g Ask for price
Description: Afatinib Dimaleate

Afatinib Dimaleate

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Description: Afatinib Dimaleate

Afatinib Dimaleate

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Description: Afatinib Dimaleate

Afatinib Dimaleate

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Description: Afatinib Dimaleate

(2Z)-Afatinib-d6

A355307 25mg
EUR 3000

Afatinib N-Oxide

A355330 25mg
EUR 1722

Afatinib N-Oxide

T10257-10mg 10mg Ask for price
Description: Afatinib N-Oxide

Afatinib N-Oxide

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Description: Afatinib N-Oxide

Afatinib N-Oxide

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Description: Afatinib N-Oxide

Afatinib N-Oxide

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Description: Afatinib N-Oxide

Afatinib N-Oxide

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Description: Afatinib N-Oxide

Afatinib impurity 11

T35430-10mg 10mg Ask for price
Description: Afatinib impurity 11

Afatinib impurity 11

T35430-1g 1g Ask for price
Description: Afatinib impurity 11

Afatinib impurity 11

T35430-1mg 1mg Ask for price
Description: Afatinib impurity 11

Afatinib impurity 11

T35430-50mg 50mg Ask for price
Description: Afatinib impurity 11

Afatinib impurity 11

T35430-5mg 5mg Ask for price
Description: Afatinib impurity 11

3-Dechloro Afatinib

D226460 250mg
EUR 3000

Afatinib-d6 Dimaleate

A355317 10mg
EUR 437

Afatinib Impurity AFT-8

A355335 100mg
EUR 1028
Description: 2323570-72-3

N3-(3-Dimethylamino,1-carboxyprop-2-yl) Afatinib

D471315 25mg
EUR 11200

EGFR/HER2 kinase inhibitor (>99%, M.wt 485.94) (Afatinib/BIBW-2992

SM-101000-5 5 mg
EUR 196.8

EGFR/HER2 kinase inhibitor (>99%, M.wt 485.94) (Afatinib/BIBW-2992

SM-101000-50 50 mg
EUR 781.2

Des(N,N-Dimethylprop-2-enyl-1-Amine) Afatinib

D291240 10mg
EUR 1631

Diethyl (S)-2-Amino-2-oxoethyl Phosphonate Afatinib

D355300 250mg
EUR 800
Description: 618061-76-0

3-Dechloro-4-defluoro 4-Chloro-3-fluoro Afatinib

D226455 100mg
EUR 3000

Deschloro-N-des(4-dimethylamino-2-en-1-oxo)butyl Afatinib

D289625 1g
EUR 1800

Desfluoro-N-des(4-dimethylamino-2-en-1-oxo)butyl Afatinib

D289815 2.5g
EUR 1800
Description: 2413212-09-4

Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol)

A355320 100mg
EUR 276
Description: 314771-76-1

Deschloro,desfluoro-N-des(4-dimethylamino-2-en-1-oxo)butyl Afatinib

D289635 2.5g
EUR 1800

Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(pyrrolidin-2,5-dion-1-yl) Afatinib

D291238 100mg
EUR 316

Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Amino-pyrrolidin-2-on-1-yl) Afatinib

D291248 10mg
EUR 759

Des-(4-dimethylamino-2-en-1-oxo)butylamino 6-(5-Hydroxy-pyrrolidin-2-on-1-yl) Afatinib

D291245 10mg
EUR 874

Afamelanotide free base

330224 1.0mg
EUR 265

I-37 free base( 2359690-13-2(free base))

T8721L-10mg 10mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))

T8721L-1g 1g Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))

T8721L-1mg 1mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))

T8721L-50mg 50mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))

T8721L-5mg 5mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

TMB free base

TB0954 1g
EUR 85.06

S107 free base

530577 100.0mg
EUR 750

THZ1 (Free base)

9664-25 each
EUR 1227.6

THZ1 (Free base)

9664-5 each
EUR 352.8

K201 free base

414202 5.0mg
EUR 288

FIPI free base

407955 200.0mg
EUR 1050

R406(free base)

E1KS1533 2mg
EUR 362.4

FIPI (free base)

B2372-25 each
EUR 757.2

FIPI (free base)

B2372-5 each
EUR 235.2

NG25 free base

562503 5.0mg
EUR 485

R406 (free base)

A5880-100 100 mg
EUR 800
Description: Syk inhibitor

R406 (free base)

A5880-25 25 mg
EUR 320
Description: Syk inhibitor

R406 (free base)

A5880-5 5 mg
EUR 80
Description: Syk inhibitor

R406 (free base)

A5880-5.1 10 mM (in 1mL DMSO)
EUR 148
Description: Syk inhibitor

R406 (free base)

A5880-S Evaluation Sample
EUR 22
Description: Syk inhibitor

R406 (free base)

HY-11108 10mM/1mL
EUR 277.2

SIS3 free base

T12923-10mg 10mg Ask for price
Description: SIS3 free base

SIS3 free base

T12923-1g 1g Ask for price
Description: SIS3 free base

SIS3 free base

T12923-1mg 1mg Ask for price
Description: SIS3 free base

SIS3 free base

T12923-50mg 50mg Ask for price
Description: SIS3 free base

SIS3 free base

T12923-5mg 5mg Ask for price
Description: SIS3 free base

R406 free base

T2467-10mg 10mg Ask for price
Description: R406 free base

R406 free base

T2467-1g 1g Ask for price
Description: R406 free base

R406 free base

T2467-1mg 1mg Ask for price
Description: R406 free base

R406 free base

T2467-50mg 50mg Ask for price
Description: R406 free base

R406 free base

T2467-5mg 5mg Ask for price
Description: R406 free base

ML355 free base

533249 50.0mg
EUR 350

ML241 free base

406621 10.0mg
EUR 90

MS023 free base

407274 10.0mg
EUR 150

LYS01 free base

407398 10.0mg
EUR 150

ML298 free base

407464 5.0mg
EUR 240

M2698 free base

407496 200.0mg
EUR 2950

AZ505 free base

407948 5.0mg
EUR 150

YM158 (free base)

HY-U00355 1mg
EUR 2770.8

YM158 free base

T10501-10mg 10mg Ask for price
Description: YM158 free base

YM158 free base

T10501-1g 1g Ask for price
Description: YM158 free base

YM158 free base

T10501-1mg 1mg Ask for price
Description: YM158 free base

YM158 free base

T10501-50mg 50mg Ask for price
Description: YM158 free base

YM158 free base

T10501-5mg 5mg Ask for price
Description: YM158 free base

MA242 free base

T62977-10mg 10mg Ask for price
Description: MA242 free base

MA242 free base

T62977-1g 1g Ask for price
Description: MA242 free base

MA242 free base

T62977-1mg 1mg Ask for price
Description: MA242 free base

MA242 free base

T62977-50mg 50mg Ask for price
Description: MA242 free base

MA242 free base

T62977-5mg 5mg Ask for price
Description: MA242 free base

CXD101 free base

581056 5.0mg
EUR 150

LXH254 free base

584644 5.0mg
EUR 150

ASN007 free base

207046 5.0mg
EUR 150

BGT226 free base

200492 5.0mg
EUR 250

Y27632 free base

341079 1.0mg
EUR 450

Oxamyl Free Base

413788 100.0mg
EUR 262

Ecabet Free Base

413988 100.0mg
EUR 248

JPH203 free base

406760 5.0mg
EUR 150

LMP744 free base

406962 50.0mg
EUR 950

LGH447 free base

407201 5.0mg
EUR 450

SHP099 free base

407376 10.0mg
EUR 150

MCC950 (Free base)

B1031-1 each
EUR 183.6

MCC950 (Free base)

B1031-5 each
EUR 548.4

LX7101 free base

522452 10.0mg
EUR 550

SR1903 free base

574023 1.0mg
EUR 210

S38093 free base

555223 100.0mg
EUR 950

ML120B free base

558369 5.0mg
EUR 90

ITI214 (free base)

HY-12501 100mg
EUR 3531.6

Hu7691 free base

T39733-10mg 10mg Ask for price
Description: Hu7691 free base

Hu7691 free base

T39733-1g 1g Ask for price
Description: Hu7691 free base

Hu7691 free base

T39733-1mg 1mg Ask for price
Description: Hu7691 free base

Hu7691 free base

T39733-50mg 50mg Ask for price
Description: Hu7691 free base

Hu7691 free base

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Description: Hu7691 free base

ZW4864 free base

T9642-10mg 10mg Ask for price
Description: ZW4864 free base

ZW4864 free base

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Description: ZW4864 free base

ZW4864 free base

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Description: ZW4864 free base

ZW4864 free base

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Description: ZW4864 free base

ZW4864 free base

T9642-5mg 5mg Ask for price
Description: ZW4864 free base

AFP464 free base

T10258-10mg 10mg Ask for price
Description: AFP464 free base

AFP464 free base

T10258-1g 1g Ask for price
Description: AFP464 free base

AFP464 free base

T10258-1mg 1mg Ask for price
Description: AFP464 free base

AFP464 free base

T10258-50mg 50mg Ask for price
Description: AFP464 free base

AFP464 free base

T10258-5mg 5mg Ask for price
Description: AFP464 free base

EF1502 free base

T27241-10mg 10mg Ask for price
Description: EF1502 free base

EF1502 free base

T27241-1g 1g Ask for price
Description: EF1502 free base

EF1502 free base

T27241-1mg 1mg Ask for price
Description: EF1502 free base

EF1502 free base

T27241-50mg 50mg Ask for price
Description: EF1502 free base

EF1502 free base

T27241-5mg 5mg Ask for price
Description: EF1502 free base

AMN082 free base

T21935L-10mg 10mg Ask for price
Description: AMN082 free base

AMN082 free base

T21935L-1g 1g Ask for price
Description: AMN082 free base

AMN082 free base

T21935L-1mg 1mg Ask for price
Description: AMN082 free base

AMN082 free base

T21935L-50mg 50mg Ask for price
Description: AMN082 free base

AMN082 free base

T21935L-5mg 5mg Ask for price
Description: AMN082 free base

SRA880 free base

T28851-10mg 10mg Ask for price
Description: SRA880 free base

SRA880 free base

T28851-1g 1g Ask for price
Description: SRA880 free base

SRA880 free base

T28851-1mg 1mg Ask for price
Description: SRA880 free base

SRA880 free base

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Description: SRA880 free base

SRA880 free base

T28851-5mg 5mg Ask for price
Description: SRA880 free base

RPC425 free base

T28614-10mg 10mg Ask for price
Description: RPC425 free base

RPC425 free base

T28614-1g 1g Ask for price
Description: RPC425 free base

RPC425 free base

T28614-1mg 1mg Ask for price
Description: RPC425 free base

RPC425 free base

T28614-50mg 50mg Ask for price
Description: RPC425 free base

RPC425 free base

T28614-5mg 5mg Ask for price
Description: RPC425 free base

SKL2001 free base

526260 50.0mg
EUR 450

Cetaben (free base)

531101 5.0mg
EUR 100

Exherin free base

201350 5.0mg
EUR 120

Symadex free base

201510 5.0mg
EUR 295

APTO253 free base

205517 5.0mg
EUR 280

AZD4573 free base

206979 5.0mg
EUR 450

Quinine (free base)

318603 2.0g
EUR 250

Nefopam Free Base

414304 1.0g
EUR 428

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