iowaodes

Single cell transcriptomes reveal expression patterns of chemoreceptor genes in olfactory sensory neurons of the Caribbean

An embedded gene selection method using knockoffs optimizing neural network

 

Background: Gene choice refers to discover a small subset of discriminant genes from the gene expression profiles. The way to choose genes that have an effect on particular phenotypic traits successfully is a vital analysis work within the subject of biology. The neural community has higher becoming capability when coping with nonlinear information, and it will probably seize options robotically and flexibly. On this work, we suggest an embedded gene choice methodology utilizing neural community.

 

The essential genes may be obtained by calculating the burden coefficient after the coaching is accomplished. In an effort to remedy the issue of black field of neural community and additional make the coaching outcomes interpretable in neural community, we use the concept of knockoffs to assemble the knockoff characteristic genes of the unique characteristic genes. This methodology not solely make every characteristic gene to compete with one another, but additionally make every characteristic gene compete with its knockoff characteristic gene. This method may help to pick the important thing genes that have an effect on the decision-making of neural networks.

 

Outcomes: We use maize carotenoids, tocopherol methyltransferase, raffinose household oligosaccharides and human breast most cancers dataset to do verification and evaluation.

 

Conclusions: The experiment outcomes display that the knockoffs optimizing neural community methodology has higher detection impact than the opposite present algorithms, and specifically for processing the nonlinear gene expression and phenotype information.

 

iowaodes
iowaodes

Fenretinide

A3412-5.1 10 mM (in 1mL DMSO)
EUR 113.00
Description: Fenretinide(4HPR) is an inhibitor of Focal adhesion kinase (FAK) [1].Fenretinideis a vitamin A analogue, it has been shown toinhibit the growth of many tumor cells, including small-cell lung cancer, malignant hemopoietic cells, and breast cancer cells.

Fenretinide

A3412-50 50 mg
EUR 152.00
Description: Fenretinide(4HPR) is an inhibitor of Focal adhesion kinase (FAK) [1].Fenretinideis a vitamin A analogue, it has been shown toinhibit the growth of many tumor cells, including small-cell lung cancer, malignant hemopoietic cells, and breast cancer cells.

Fenretinide

HY-15373 10mM/1mL
EUR 126.00

Fenretinide

GP8861-10MG 10 mg
EUR 94.00

Fenretinide

GP8861-25MG 25 mg
EUR 142.00

 

Single cell transcriptomes reveal expression patterns of chemoreceptor genes in olfactory sensory neurons of the Caribbean spiny lobster, Panulirus argus

 

 

Background: Crustaceans categorical a number of courses of receptor genes of their antennules, which home olfactory sensory neurons (OSNs) and non-olfactory chemosensory neurons. Transcriptomics research reveal that candidate chemoreceptor proteins embrace variant Ionotropic Receptors (IRs) together with each co-receptor IRs and tuning IRs, Transient Receptor Potential (TRP) channels, Gustatory Receptors, epithelial sodium channels, and sophistication A G-protein coupled receptors (GPCRs). The Caribbean spiny lobster, Panulirus argus, expresses in its antennules almost 600 IRs, 17 TRP channels, 1 Gustatory Receptor, 7 epithelial sodium channels, 81 GPCRs, 6 G proteins, and dozens of enzymes in signaling pathways.

 

Nevertheless, the precise combinatorial expression patterns of those proteins in single sensory neurons usually are not recognized for any crustacean, limiting our understanding of how their chemosensory techniques encode chemical high quality.

 

Outcomes: The purpose of this research was to make use of transcriptomics to explain expression patterns of chemoreceptor genes in OSNs of P. argus. We generated and analyzed transcriptomes from 7 single OSNs, a few of which have been proven to answer a meals odor, in addition to a further 7 multicell transcriptomes from preparations containing few (2-4), a number of (ca. 15), or many (ca. 400) OSNs. We discovered that every OSN expressed the identical 2 co-receptor IRs (IR25a, IR93a) however

 

not the opposite 2 antennular coIRs (IR8a, IR76b), 9-53 tuning IRs however just one to some in excessive abundance, the identical 5 TRP channels plus as much as 5 extra TRPs, 12-17 GPCRs together with the identical 5 expressed in each single cell transcriptome, the identical Three G proteins plus others, many enzymes within the signaling pathways, however no Gustatory Receptors or epithelial sodium channels. The best distinction in receptor expression among the many OSNs was the identification of the tuning IRs.

 

Conclusions: Our outcomes present an preliminary view of the combinatorial expression patterns of receptor molecules in single OSNs in a single species of decapod crustacean, together with receptors straight concerned in olfactory transduction and others doubtless concerned in modulation. Our outcomes additionally counsel variations in receptor expression in OSNs vs. different chemosensory neurons.

Camel Genetic Assets Conservation by Tourism: A Key Sociocultural Method of Camelback Leisure Driving

 

  • Camels are unique parts, which may be comprised inside journey journey corporations selling ecotourism actions. Such recreations contribute to sustainable livelihoods for native communities and academic empowerment in the direction of nature and its conservation. At current, some native camel breeds’ survival reduces to this animal-based leisure business and its reliability to carry out and promote custom-made companies By conducting an on-site questionnaire to prospects taking part in camelback driving excursions, we assessed the motivational components affecting participation, satisfaction, and loyalty on this tourism phase that will have made it socially differentiated.

 

  • The sixfold mixture of workers efficiency, tradition geography, numerous and humane shut interplay, camel conduct and efficiency, sociotemporal context, and constructive earlier expertise includes the fundamental dimensions that designate buyer satisfaction and return intention chance inside this leisure enterprise.

 

  • Buyer data is crucial for stakeholders to construct personalised driving experiences and align income with environmental sustainability and biodiversity mainstream considerations into their on a regular basis operations. In flip, home camel vacationer rides might be managed as a viable path to nature conservation by serving to endangered native breeds to keep away from their useful devaluation and potential extinction.

 

gel casting base 20 cm

EVS1300-BASE ea
EUR 200.00

gel casting base for evs3100

EVS3100-BASE ea
EUR 301.00

gel casting base for evs3200

EVS3200-BASE ea
EUR 301.00

gel casting base for evs3300

EVS3300-BASE ea
EUR 301.00

Carubicin (Free base)

B1853-1
EUR 153.00

Carubicin (Free base)

B1853-5
EUR 457.00

FIPI (free base)

B2372-25
EUR 631.00

FIPI (free base)

B2372-5
EUR 196.00

Terbinafine (Free base)

B2423-250
EUR 207.00

Terbinafine (Free base)

B2423-50
EUR 120.00

MCC950 (Free base)

B1031-1
EUR 153.00

MCC950 (Free base)

B1031-5
EUR 457.00

Apatinib (Free base)

B1613-25
EUR 414.00

Apatinib (Free base)

B1613-5
EUR 142.00

AZD4547, Free Base

ADC-P-063 unit Ask for price

AZD8055, Free Base

ADC-P-064 unit Ask for price

Cyclopamine, Free Base

ADC-P-079 unit Ask for price

Ixabepilone, Free Base

ADC-P-104 unit Ask for price

R406(free base)

E1KS1533 2mg
EUR 521.00

RPR107393 free base

HY-100299 1mg
EUR 481.00

FR167344 free base

HY-100301 1mg
EUR 2637.00

FR183998 free base

HY-100302 1mg
EUR 1127.00

FR194738 free base

HY-100303 1mg
EUR 1990.00

Vatalanib (free base)

HY-10203 5mg
EUR 119.00

Masupirdine (free base)

HY-109118 1mg
EUR 223.00

R406 (free base)

HY-11108 10mM/1mL
EUR 231.00

ITI214 (free base)

HY-12501 100mg
EUR 2943.00

AS2863619 (free base)

HY-126675 5mg
EUR 1175.00

AZD3839 (free base)

HY-13438 50mg
EUR 1014.00

Ripasudil free base

HY-15685A 10mg
EUR 408.00

YM158 (free base)

HY-U00355 1mg
EUR 2309.00

THZ1 (Free base)

9664-25
EUR 1023.00

THZ1 (Free base)

9664-5
EUR 294.00

LY2835219 free base

A3575-100 100 mg
EUR 572.00
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

LY2835219 free base

A3575-25 25 mg
EUR 258.00
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

LY2835219 free base

A3575-5 5 mg
EUR 142.00
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

R406 (free base)

A5880-100 100 mg
EUR 1210.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-25 25 mg
EUR 514.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-5 5 mg
EUR 166.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-5.1 10 mM (in 1mL DMSO)
EUR 264.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-S Evaluation Sample
EUR 81.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

Rucaparib (free base)

A8893-10 10 mg
EUR 200.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-200 200 mg
EUR 1036.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-5 5 mg
EUR 137.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-5.1 10 mM (in 1mL DMSO)
EUR 142.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-50 50 mg
EUR 456.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Lapatinib, Free base

2138-100
EUR 387.00

Lapatinib, Free base

2138-25
EUR 191.00

Ruxolitinib, Free base

2139-100 Ask for price

Ruxolitinib, Free base

2139-25
EUR 533.00

Ruxolitinib, Free base

2139-5
EUR 207.00

Imatinib, Free base

2141-100
EUR 147.00

Imatinib, Free base

2141-1000
EUR 419.00

Linsitinib, Free base

2294-25
EUR 566.00

Linsitinib, Free base

2294-5
EUR 185.00

Tipifarnib, Free base

2296-1
EUR 142.00

Tipifarnib, Free base

2296-5
EUR 414.00

Vatalanib, Free Base

2026-25
EUR 305.00

Vatalanib, Free Base

2026-5
EUR 126.00

Erlotinib, Free Base

2048-100
EUR 158.00

Erlotinib, Free Base

2048-1000
EUR 387.00

Sunitinib, Free base

2097-100
EUR 191.00

Sunitinib, Free base

2097-1000
EUR 501.00

Sunitinib, Free base

2097-25
EUR 115.00

Xylazine (free base)

Q-1445.0025 25.0g
EUR 321.00
Description: Sum Formula: C12H16N2S; CAS# [7361-61-7]

TMB free base

TB0954 1g
EUR 70.88
  • Product category: Biochemicals/Indicators/Stains/Immuno Related

PLX5622 (free base)

B2965-25 25 mg
EUR 753.00

PLX5622 (free base)

B2965-5 5 mg
EUR 227.00

BMS-345541 (Free base)

B1907-1
EUR 142.00

BMS-345541 (Free base)

B1907-5
EUR 414.00

UNC-926, free base

B2158-25
EUR 631.00

UNC-926, free base

B2158-5
EUR 196.00

SB-334867 free base

B3423-100 100 mg
EUR 599.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base

B3423-25 25 mg
EUR 290.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base

B3423-5 5 mg
EUR 128.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base

B3423-5.1 10 mM (in 1mL DMSO)
EUR 131.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

GSK J4 free base

B5959-10 10 mg
EUR 373.00
Description: GSK J4 free base

GSK J4 free base

B5959-50 50 mg
EUR 1198.00
Description: GSK J4 free base

BMS-345541(free base)

B4655-10 10 mg
EUR 235.00
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

BMS-345541(free base)

B4655-5 5 mg
EUR 171.00
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

BMS-345541(free base)

B4655-50 50 mg
EUR 595.00
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

Staurosporine, >99% Free Base

BC090-001 1mg
EUR 246.00

Staurosporine, >99% Free Base

BC090-005 5mg
EUR 340.00

Vandetanib, >99% Free Base

BC098-025 25mg
EUR 232.00

Vandetanib, >99% Free Base

BC098-050 50mg
EUR 286.00

Vandetanib, >99% Free Base

BC098-100 100mg
EUR 313.00

Vandetanib, >100% Free Base

BC098-500 500mg
EUR 658.00

FK-448 Free base

HY-100193 10mg
EUR 1887.00

KW-8232 free base

HY-100304 10mg
EUR 5018.00

YM-53601 free base

HY-100313 1mg
EUR 1559.00

AV-412 (free base)

HY-10346A 5mg
EUR 173.00

SB-334867 (free base)

HY-10895A 10mg
EUR 215.00

SNT-207858 (free base)

HY-11030A 10mg
EUR 911.00

DOV-216,303 (Free Base)

HY-18332C 10mM/1mL
EUR 492.00

APX-115 (free base)

HY-120801A 5mg
EUR 223.00

LY-2584702 (free base)

HY-12493 5mg
EUR 165.00

Genz-123346 (free base)

HY-12744 10mM/1mL
EUR 189.00

YHO-13351 (free base)

HY-12758A 10mM/1mL
EUR 176.00

JTV-519 (free base)

HY-15293A 5mg
EUR 567.00

RGB-286638 (free base)

HY-15504A 100mg
EUR 2804.00

CP-319340(free base)

HY-U00270 5mg
EUR 877.00

SGI-1776 free base

A4192-10 10 mg
EUR 247.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-5 5 mg
EUR 154.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-5.1 10 mM (in 1mL DMSO)
EUR 166.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-50 50 mg
EUR 525.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-S Evaluation Sample
EUR 81.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

AM-095 free base

A3167-10 10 mg
EUR 212.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-100 100 mg
EUR 804.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-200 200 mg
EUR 1152.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-5 5 mg
EUR 166.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-50 50 mg
EUR 572.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

L-Arginine free base

AB0205 100g
EUR 63.15
  • Product category: Biochemicals/Amino Acids/Derivatives

RGB-286638,  free base

2886-25
EUR 756.00

RGB-286638,  free base

2886-5
EUR 229.00

StemRegenin 1, Free base

2642-1
EUR 131.00

StemRegenin 1, Free base

2642-5
EUR 332.00

GSK-J4 (Free base)

2762-1
EUR 120.00

GSK-J4 (Free base)

2762-5
EUR 262.00

Z-NHNH2 (free base)

Q-1150.0025 25.0g
EUR 126.00
Description: Sum Formula: C8H10N2O2; CAS# [5331-43-1]

Z-NHNH2 (free base)

Q-1150.0100 100.0g
EUR 321.00
Description: Sum Formula: C8H10N2O2; CAS# [5331-43-1]

Afatinib

HY-10261 200mg
EUR 312.00

Afatinib

A170-100MG 100mg
EUR 102.00

SB 202190, >99% Free Base

BC086-025 25mg
EUR 205.00

SB 202190, >99% Free Base

BC086-050 50mg
EUR 246.00

SB 203580, >99% Free Base

BC087-025 25mg
EUR 219.00

SB 203580, >99% Free Base

BC087-050 50mg
EUR 286.00

Gastrofensin AN 5 free base

HY-100296 5mg
EUR 2120.00

Bay 65-1942 (free base)

HY-50949 10mg
EUR 1069.00

Glyoxalase I inhibitor (free base)

HY-15167A 50mg
EUR 2530.00

Biotin ethylenediamine (free base form)

90071 25MG
EUR 132.00
Description: Minimum order quantity: 1 unit of 25MG

biotin cadaverine, free base form

90079 50MG
EUR 215.00
Description: Minimum order quantity: 1 unit of 50MG

BAY 43-9006, Free base

2142-100
EUR 419.00

BAY 43-9006, Free base

2142-25
EUR 169.00

BAY 58-2667 (Free base)

2452-1
EUR 354.00

BAY 58-2667 (Free base)

2452-5
EUR 1132.00

EZSolution? StemRegenin 1, Free base

2643-1
EUR 142.00

H-Tyr-OEt (free base)

E-2900.0025 25.0g
EUR 139.00
Description: Sum Formula: C11H15NO3; CAS# [949-67-7]

H-Tyr-OEt (free base)

E-2900.0100 100.0g
EUR 357.00
Description: Sum Formula: C11H15NO3; CAS# [949-67-7]

Afatinib (dimaleate)

HY-10261A 200mg
EUR 312.00

Afatinib dimaleate

A3145-10 10 mg
EUR 221.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib dimaleate

A3145-5 5 mg
EUR 147.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib dimaleate

A3145-5.1 10 mM (in 1mL DMSO)
EUR 119.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib dimaleate

A3145-50 50 mg
EUR 512.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib (BIBW2992)

A8247-10 10 mg
EUR 221.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-5 5 mg
EUR 147.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-5.1 10 mM (in 1mL DMSO)
EUR 244.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-50 50 mg
EUR 512.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-S Evaluation Sample
EUR 81.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Human Free PSA (f-PSA) ELISA Kit

PRB-5049-FREE 96 assays
EUR 572.00

PNU-282987 (S enantiomer free base)

HY-12560D 5mg
EUR 1014.00

Cyclosporin A-Derivative 1 (Free base)

HY-P1355A 1mg
EUR 223.00

biotin-x cadaverine, free base form

90080 20MG
EUR 215.00
Description: Minimum order quantity: 1 unit of 20MG

H-Arg(Mtr)-OtBu (free base)

E-3075.0001 1.0g
EUR 309.00
Description: Sum Formula: C20H34N4O5S; CAS# [115608-61-2]

H-Arg(Mtr)-OtBu (free base)

E-3075.0005 5.0g
EUR 1143.00
Description: Sum Formula: C20H34N4O5S; CAS# [115608-61-2]

H-Arg(Pmc)-OtBu (free base)

E-3085.0001 1.0g
EUR 418.00
Description: Sum Formula: C24H40N4O5S; CAS# [169543-81-1]

H-Arg(Pmc)-OtBu (free base)

E-3085.0005 5.0g
EUR 1554.00
Description: Sum Formula: C24H40N4O5S; CAS# [169543-81-1]

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-002 2 mg
EUR 178.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-005 5 mg
EUR 265.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-010 10 mg
EUR 315.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-025 25 mg
EUR 394.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-100 100 mg
EUR 887.00

H-Ala-Ala-Phe-AMC (free base)

I-1415.0050 50.0mg
EUR 151.00
Description: Sum Formula: C25H28N4O5; CAS# [62037-41-6]

H-Ala-Ala-Phe-AMC (free base)

I-1415.0250 250.0mg
EUR 515.00
Description: Sum Formula: C25H28N4O5; CAS# [62037-41-6]

Human Free PSA (f-PSA) ELISA Kit

PRB-5049-FREE-5 5 x 96 assays
EUR 2283.00

(D-Ser(tBu)6,Azagly10)-LHRH (free base)

H-7296.0005 5.0mg
EUR 183.00
Description: Sum Formula: C59H84N18O14; CAS# [65807-02-5]

(D-Ser(tBu)6,Azagly10)-LHRH (free base)

H-7296.0025 25.0mg
EUR 641.00
Description: Sum Formula: C59H84N18O14; CAS# [65807-02-5]

casting base

EHS3100-CAST ea
EUR 107.00

casting base

EHS3200-CAST ea
EUR 124.00

casting base

EHS3300-CAST ea
EUR 124.00

Rimonabant base

GX9120-10MG 10 mg
EUR 86.00

Rimonabant base

GX9120-25MG 25 mg
EUR 130.00

Tetracycline base

GA9779-100G 100 g
EUR 150.00

Tetracycline base

GA9779-10G 10 g
EUR 46.00

Tetracycline base

GA9779-25G 25 g
EUR 62.00

Tris-base

20-abx082498
  • EUR 328.00
  • EUR 203.00
  • EUR 411.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

ProteoIQ Base

PS2 1
EUR 4262.00

Vincamine base

Q-1435.0005 5.0g
EUR 225.00
Description: Sum Formula: C21H26N2O3; CAS# [1617-90-9]

Vincamine base

Q-1435.0025 25.0g
EUR 803.00
Description: Sum Formula: C21H26N2O3; CAS# [1617-90-9]

CETRIMIDE AGAR BASE

C03-107-10kg 10 kg
EUR 1229.00

CETRIMIDE AGAR BASE

C03-107-2Kg 2 Kg
EUR 306.00

CETRIMIDE AGAR BASE

C03-107-500g 500 g
EUR 120.00

Fuchsine base (monohydrochloride)

HY-B1539A 1g
EUR 119.00

Rhodamine B base

GT5360-100G 100 g
EUR 158.00

Rhodamine B base

GT5360-10G 10 g
EUR 50.00

Rhodamine B base

GT5360-25G 25 g
EUR 70.00

Rhodamine B base

GT5360-50G 50 g
EUR 102.00

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